143979-44-6 Usage
Uses
Used in Chemical Synthesis:
3-Phenyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester is used as a chemical intermediate for the synthesis of various complex organic molecules. Its unique structure allows for versatile reactions, making it a valuable component in the development of new compounds and materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Phenyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester is used as a building block for the creation of novel drug molecules. Its potential in medicinal chemistry is attributed to its ability to form stable bonds with other molecules, facilitating the design of new therapeutic agents.
Used in Material Science:
3-Phenyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester is employed as a component in the development of advanced materials, such as polymers and composites. Its incorporation into these materials can enhance their properties, such as strength, flexibility, and durability, making them suitable for various applications, including aerospace, automotive, and electronics industries.
Used in Research and Development:
3-Phenyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester is utilized as a research compound in academic and industrial laboratories. Its unique properties and potential applications make it an interesting subject for studies aimed at understanding its chemical behavior and exploring new uses in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 143979-44-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,9,7 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 143979-44:
(8*1)+(7*4)+(6*3)+(5*9)+(4*7)+(3*9)+(2*4)+(1*4)=166
166 % 10 = 6
So 143979-44-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H21NO4/c1-16(2,3)21-15(20)17-10-9-12(13(17)14(18)19)11-7-5-4-6-8-11/h4-8,12-13H,9-10H2,1-3H3,(H,18,19)
143979-44-6Relevant academic research and scientific papers
Access to enantiomerically pure cis- and trans-β-phenylproline by high-performance liquid chromatography resolution
Fatás, Paola,Gil, Ana M.,Calaza, M. Isabel,Jiménez, Ana I.,Cativiela, Carlos
, p. 1082 - 1091 (2013/02/22)
The preparation of all four stereoisomers of the proline analog that bears a phenyl group attached to the β carbon either cis or trans to the carboxylic acid (cis- and trans-β-phenylproline, respectively) has been addressed. The methodology developed allows access to multigram quantities of the target amino acids in enantiomerically pure form and suitably protected for use in peptide synthesis. Racemic precursors of cis-β-phenylproline and trans-β-phenylproline were prepared from easily available starting materials and subjected to high-performance liquid chromatography enantioseparation. Semipreparative columns (250 × 20 mm) containing chiral stationary phases based on amylose (Chiralpak IA) (Daicel-Chiral Technologies Europe, Illkirch, France) or cellulose (Chiralpak IC) were used respectively for the resolution of the cis- and trans-β-phenylproline precursors. Chirality, 24:1082-1091, 2012. 2012 Wiley Periodicals, Inc. Copyright
PIPERIDINE AND PYRROLIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
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Page/Page column 36, (2008/06/13)
The present invention is directed to compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
