1442007-65-9

Upstream product

• 1083308-96-6 (1S)-2,2,5,5-tetramethylcyclohex-3-en-1-ol 
• 15500-76-2 Dimethyl-dimedon-mono-(toluol-4-sulfonyl-hydrazon) 
• 702-50-1 2,2,5,5-tetramethylcyclohexa-1,3-dione 
• 124-63-0 methanesulfonyl chloride 
• 13855-90-8 2,2,5,5-tetramethylcyclohex-3-en-1-one 

Relevant academic research and scientific papers

Syntheses of racemic and scalemic cis-chrysanthemic acid from β,γ-unsaturated cyclohexanol

2,2,5,5-Tetramethylcyclohexane-1,3-dione is a valuable starting-material precursor of cis-chrysanthemic acid. The (1S)-stereoisomer is a precursor of pyrethrin I, the most active natural insecticide from Chrysanthemum cinerariifolium, whereas the (1R)-stereoisomer is efficiently transformed to deltamethrin, the most active commercially available pyrethroid insecticide. Several intermediates have been identified and used with variable success for that purpose.