14428-98-9

Basic information

• Product Name: 1-phenyl-N-[(1E)-1-phenylethylidene]methanamine
• CAS NO: 14428-98-9
• Molecular Formula: C₁₅H₁₅N
• Molecular Weight: 209.2863
• Mol File: 14428-98-9.mol
• Article Data: 72

Chemical Properties

• Boiling Point: 305.1°C at 760 mmHg
• Flash Point: 130.3°C
• Density: 0.94g/cm³
• Vapor Pressure: 0.00152mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: 1-phenyl-N-[(1E)-1-phenylethylidene]methanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-N-[(1E)-1-phenylethylidene]methanamine(14428-98-9)
• EPA Substance Registry System: 1-phenyl-N-[(1E)-1-phenylethylidene]methanamine(14428-98-9)

Safety Data

• Hazardous Substances Data: 14428-98-9(Hazardous Substances Data)

Usage

Aromatic amine derivative

This compound belongs to the class of aromatic amines, which are derivatives containing an amine functional group (-NH2) and an aromatic ring in their structure.

Phenyl group attached to nitrogen atom

A phenyl group (a ring of six carbon atoms with alternating single and double bonds) is directly attached to the nitrogen atom in this compound.

Ethylidene substituent

The compound contains an ethylidene group (-CH=) as a substituent, which is a vinyl group without the hydrogen atom.

Another phenyl group in the ethylidene substituent

The ethylidene group in the compound is attached to another phenyl group, forming a (1E)-1-phenylethylidene structure.

Potential applications in organic synthesis

1-phenyl-N-[(1E)-1-phenylethylidene]methanamine can be used as a reagent in the production of other organic compounds, making it valuable in the field of organic synthesis.

Possible uses in pharmaceutical research

Although not extensively studied, this complex chemical compound may have potential applications in pharmaceutical research due to its unique structure and properties.

Complex chemical compound

1-phenyl-N-[(1E)-1-phenylethylidene]methanamine is a complex chemical compound with a variety of functional groups and structures, which may contribute to its potential industrial and research applications.

Upstream product

• 123-91-1 1,4-dioxane 
• 64-17-5 ethanol 
• 3129-98-4 (R)-benzylidene-(1-phenylethyl)amine 
• 141-52-6 sodium ethanolate 
• 17480-71-6 N-benzylidene-α-methylbenzylamine 
• 52826-45-6 (benzylimino)triphenylphosphorane 
• 98-86-2 acetophenone 
• 622-79-7 benzyl azide 
• 98-85-1 1-Phenylethanol 
• 100-46-9 benzylamine 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 536-74-3 phenylacetylene 
• 97325-80-9 1-Benzyl-4,5-dimethyl-5-phenyl-4,5-dihydro-1H-tetrazole 
• 100-47-0 benzonitrile 

Downstream Products

• 6624-04-0 2-benzyl-1,3-diphenyl-propan-1-one 
• 17480-69-2 (S)-N-benzyl-1-phenylethylamine 
• 56249-47-9 2-(benzylamino)-2-phenylpropanenitrile 
• 779-54-4 (S)-N-phenyl-1-phenylethylamine 
• 779-54-4 (R)-phenyl-(1-phenylethyl)amine 
• 38235-77-7 (R)-N-benzyl-1-phenylethylamine 

Relevant articles and documents

Rh(I)-catalyzed solvent-free ortho-alkylation of aromatic imines under microwave irradiation

The synthesis of ortho-alkylated ketones through a chelation-assisted Rh (I) catalyzed ortho-alkylation reaction of aromatic imines under microwave activated solvent-free conditions in monomode reactors was performed. These conditions have been also applied to hydroacylation and ortho-alkylation reactions with aldimines.

Base-Catalyzed [3 + 2] Cycloaddition of N-Benzyl Ketimines to Arylacetylenes Followed by Oxidation: A One-Pot Access to Polyarylated 2 H-Pyrroles via Intermediate Pyrrolines

N-Benzyl ketimines undergo [3 + 2] cycloaddition with arylacetylenes in the KOBut/DMSO solution to 2,3,5-triarylpyrrolines, which are oxidized (chloranil, DDQ) in situ to 2,3,5-triaryl-2H-pyrroles in 53-71% yields. The intermediate 1-pyrrolines can be isolated in 31-91% yields and separately oxidized to the corresponding 2H-pyrroles.

Enantioselective reduction of: N -alkyl ketimines with frustrated Lewis pair catalysis using chiral borenium ions

Enantioselective reduction of ketimines was demonstrated using chiral N-heterocyclic carbene (NHC)-stabilised borenium ions in frustrated Lewis pair catalysis. High levels of enantioselectivity were achieved for substrates featuring secondary N-alkyl substituents. Comparative reactivity and mechanistic studies identify key determinants required to achieve useful enantioselectivity and represent a step forward in the further development of enantioselective FLP methodologies.