1443446-80-7Relevant academic research and scientific papers
Development of a Synthetic Method for Multifunctionalized Pyrroles Using Isocyanide Dichloride as a Key Intermediate
Soeta, Takahiro,Matsumoto, Akihiro,Ukaji, Yutaka
, p. 4831 - 4834 (2018/04/26)
Multifunctionalized pyrrole derivatives were synthesized using a highly efficient method based on the Michael addition of carbanions generated in situ from isocyanide dichloride to α,β-unsaturated carbonyl compounds. The reactions proceeded smoothly to afford the pyrrole derivatives in good to high yields. A wide range of Michael acceptors, such as α,β-unsaturated carbonyl compounds and nitroolefin, were successfully applied to this reaction.
Silver-catalyzed isocyanide-alkyne cycloaddition: A general and practical method to oligosubstituted pyrroles
Liu, Jianquan,Fang, Zhongxue,Zhang, Qian,Liu, Qun,Bi, Xihe
supporting information, p. 6953 - 6957 (2013/07/25)
Ag2CO3 is the key: The transition-metal-catalyzed cycloaddition of isocyanides and unactivated terminal alkynes has been realized with Ag2CO3 as a unique and robust catalyst (see scheme). The protocol is highly
