144460-98-0Relevant academic research and scientific papers
Functionality transfer from C8 to C9 in sesquiterpenes. Synthesis of the named Herbolide E from artemisin
Blay, Gonzalo,Cardona, Luz,Garcia, Begona,Pedro, Jose R.
, p. 5253 - 5256 (1992)
The key intermediate 6 was obtained in five steps from artemisin (1). The spectroscopic characteristics of the synthetic product 7a reveal that the proposed structure for the natural herbolide E must be revised.
Synthesis of the Reported Structure of Herbolide I and Its C-11 Epimer from Artemisin
Blay, Gonzalo,Cardona, Luz,Garcia, Begona,Pedro, Jose R.
, p. 7204 - 7208 (2007/10/02)
Artemisin (1) was converted into 12 (the reported structure for herbolide I) and its C-11 epimer 19 via a synthetic pathway involving a functionality transfer from C-8 to C-9 and an A-ring refunctionalization.The 1H and 13C NMR data of synthetic products
