144467-97-0

Basic information

• Product Name: Silanol, dimethyl(1-methyl-1-phenylethyl)-
• CAS NO: 144467-97-0
• Molecular Formula: C11H18OSi
• Molecular Weight: 194.349
• Mol File: 144467-97-0.mol

Chemical Properties

• CAS DataBase Reference: Silanol, dimethyl(1-methyl-1-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Silanol, dimethyl(1-methyl-1-phenylethyl)-(144467-97-0)
• EPA Substance Registry System: Silanol, dimethyl(1-methyl-1-phenylethyl)-(144467-97-0)

Safety Data

• Hazardous Substances Data: 144467-97-0(Hazardous Substances Data)

Usage

Uses

Used in Silicone-based Material Production:
Silanol, dimethyl(1-methyl-1-phenylethyl)is used as a precursor in the production of silicone-based materials, such as adhesives and sealants, for its ability to form strong bonds with various substrates. This property makes it valuable in creating durable and versatile products that adhere well to different surfaces.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, silanol, dimethyl(1-methyl-1-phenylethyl)may be used as an ingredient in certain formulations due to its potential interactions with biological systems. Its unique structure could offer specific benefits in the development of pharmaceutical products, although further research would be required to explore these possibilities.
Used in Cosmetic Industry:
Similarly, in the cosmetic industry, silanol, dimethyl(1-methyl-1-phenylethyl)could be utilized in the formulation of various cosmetic products. Its properties might contribute to the development of innovative products with improved performance or novel effects.

Upstream product

• 17993-95-2 phenyl(1-hydroxy-1-methylethyl)dimethylsilane 
• 118740-38-8 chloro(α,α-dimethylbenzyl)dimethylsilane 

Downstream Products

• 221325-34-4 (α,α-dimethyl-4-nitrobenzyl)dimethylsilanol 
• 221325-35-5 chloro(α,α-dimethyl-4-nitrobenzyl)dimethylsilane 
• 221325-43-5 N-(9-fluorenylmethoxycarbonyl)-O-[(4-amino-α,α-dimethylbenzyl)dimethylsilyl]-L-serine allyl ester 
• 221325-37-7 N-(9-fluorenylmethoxycarbonyl)-O-[(α,α-dimethyl-4-nitrobenzyl)dimethylsilyl]-L-serine allyl ester 
• 221325-38-8 N-(9-fluorenylmethoxycarbonyl)-O-[(α,α-dimethyl-4-nitrobenzyl)dimethylsilyl]-L-threonine allyl ester 
• 221325-44-6 N-(9-fluorenylmethoxycarbonyl)-O-[(α,α-dimethyl-4-succin-monoamidobenzyl)dimethylsilyl]-L-serine allyl ester 
• 248927-82-4 N-(9-fluorenylmethoxycarbonyl)-O-[2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-6-O-(α,α-dimethyl-4-nitrobenzyl)dimethylsilyl-α-D-galactopyranosyl]-L-threonine allyl ester 

Relevant articles and documents

A novel silyl linker: Motif for side chain tethered approach to solid- phase glycopeptide synthesis

In order to facilitate the solid-phase syntheses of protected glycopeptide blocks, we designed a novel silyl linker, which allows the alcoholic side chain (carbohydrate, serine, or threonine) of (glyco-)peptides to link to the solid support. Utilizing this linker, peptide coupling reactions at both the N- and the C-termini were successful. Synthesis of the glycophorin AM fragment corresponding to the N-terminal glycoheptapeptide is demonstrated.

Rearrangements of Organosilicon Compounds Using Organoaluminum Reagents. Conversion of Phenyl- and Alkenyl(chloromethyl)silanes to Benzyl- and Allylsilanes

Various (chloromethyl)silanes undergo Wagner-Meerwein-type rearrangements using a catalytic amount of EtAlCl2 in dichloromethane.The resulting chlorosilanes have been converted to alkyl(or aryl)silanes with RMgX and/or to fluorosilanes with NH4HF2.In this way phenyl-, alkenyl-, and allyl(chloromethyl)silanes were converted to benzyl-, allyl-, and homoallylsilanes, respectively.Attempted rearrangements of methyl-, alkynyl-, and furyl(chloromethyl)silanes under these conditions were not successful.