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methyl 3-(4-((2-(2-cyanoethyl)phenyl)ethynyl)-2-fluorophenyl)propanoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1445166-50-6

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1445166-50-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1445166-50-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,5,1,6 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1445166-50:
(9*1)+(8*4)+(7*4)+(6*5)+(5*1)+(4*6)+(3*6)+(2*5)+(1*0)=156
156 % 10 = 6
So 1445166-50-6 is a valid CAS Registry Number.

1445166-50-6Relevant academic research and scientific papers

Discovery of TUG-770: A highly potent free fatty acid receptor 1 (FFA1/GPR40) agonist for treatment of type 2 diabetes

Christiansen, Elisabeth,Hansen, Steffen V. F.,Urban, Christian,Hudson, Brian D.,Wargent, Edward T.,Grundmann, Manuel,Jenkins, Laura,Zaibi, Mohamed,Stocker, Claire J.,Ullrich, Susanne,Kostenis, Evi,Kassack, Matthias U.,Milligan, Graeme,Cawthorne, Michael A.,Ulven, Trond

, p. 441 - 445 (2013/07/11)

Free fatty acid receptor 1 (FFA1 or GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and currently attracts high interest as a new target for the treatment of type 2 diabetes. We here report the discovery of a highly potent FFA1 agonist with favorable physicochemical and pharmacokinetic properties. The compound efficiently normalizes glucose tolerance in diet-induced obese mice, an effect that is fully sustained after 29 days of chronic dosing.

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