144527-89-9

Upstream product

• 31469-15-5 1-methoxy-2-methyl-1-trimethylsiloxy-1-propene 
• 100-52-7 benzaldehyde 
• 14468-90-7 N-trimethylsilyl-pyrrolidin-2-one 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 14044-65-6 borane-THF 
• 2754-27-0 trimethylsilyl acetate 
• 66183-24-2 1,5-anhydro-4,6-O-benzylidene-2-deoxy-D-erythro-hex-3-ulo-1-enitol 

Downstream Products

• 61866-20-4 methyl 3-hydroxy-2,2-dimethyl-3-phenylpropanoate 

Relevant academic research and scientific papers

Lewis acid-containing mesoporous molecular sieves as solid efficient catalysts for solvent-free Mukaiyama-type aldol condensation

The activity of the titanium mesoporous molecular sieve Ti-MCM-41 and amorphous Ti-silicate materials for carbon-carbon bond formation in the Mukaiyama aldol-type reaction between benzaldehyde and methyl trimethylsilyl dimethylketene acetal was studied an

Quaternary ammonium dendrimers as Lewis base catalysts for Mukaiyama-Aldol reaction

Surface-alkylated poly(propylene imine) dendrimer was treated with methyl iodide to afford quaternarized ammonium iodide dendrimer. The quaternarized dendrimer catalyzed the Mukaiyama-Aldol reaction of trimethylsilyl acetal with various aldehydes as a Lew

Bis(hydroxyphenyloxazolinato)-titanium(IV) and -zirconium(IV) triflates as novel transition metal-based Lewis acids

The preparation of novel titanium, 3, and zirconium, 4, organometallic Lewis acids by treatment of the readily available complexes (M = Ti, Zr; L = hydroxyphenyl-4,5-dihydrooxazole) with AgOSO2CF3 are described.The new homogeneous organometal

Synthesis of C-glycosides from glycals or vinylogous lactones and trimethylsilyl ketene acetals

2,3-Unsaturated C-glycosides were obtained in good to excellent yields from the trimethylsilyltriflate catalyzed reaction between carbohydrate derived cyclic enolethers ('glycals') and trimethylsilyl ketene acetals; under similar conditions vinylogous lac

Chain propagation determines the chemo- And regioselectivity of alkyl radical additions to C-O: Vs. C-C double bonds

Investigations into the selectivity of intermolecular alkyl radical additions to C-O- vs. C-C-double bonds in α,β-unsaturated carbonyl compounds are described. Therefore, a photoredox-initiated radical chain reaction is explored, where the activation of the carbonyl-group through an in situ generated Lewis acid-originating from the substrate-enables the formation of either C-O or the C-C-addition products. α,β-Unsaturated aldehydes form selectively 1,2-, while esters and ketones form the corresponding 1,4-addition products exclusively. Computational studies lead to reason that this chemo- and regioselectivity is determined by the consecutive step, i.e. an electron transfer, after reversible radical addition, which eventually propagates the radical chain.

Synthesis of Cage-Shaped Aluminum Aryloxides: Efficient Lewis Acid Catalyst for Stereoselective Glycosylation Driven by Flexible Shift of Four- To Five-Coordination

Monomeric cage-shaped aluminum aryl oxides 1Al were synthesized using tripodal triphenolic ligands. The Lewis acidity and catalytic activity of the obtained 1Al·py were investigated. The Lewis acidity of 1Al·py originates from the flexible change in the c

Synthesis, characterization, and properties of a benzofuran-based cage-shaped borate: Photo activation of Lewis acid catalysts

A cage-shaped borate with benzofuran moieties was synthesized. This borate showed a higher degree of catalytic activity for Mukaiyama-aldol type reactions than a simple benzene-based cage-shaped borate induced by self-aggregation. Moreover, the exposure of the complex to black-light irradiation enhanced the catalytic activity.

Mesoporous aluminosilicate-catalyzed Mukaiyama aldol reaction of aldehydes and acetals

A mesoporous aluminosilicate (Al-MCM-41) was found to be an effective heterogeneous catalyst for the reaction of both aldehydes and acetals with silyl enol ethers or ketene silyl acetals to give the corresponding aldol adducts in moderate to high yields. The remarkable high catalytic activity of Al-MCM-41 over amorphous silica-alumina and aluminum-free mesoporous silicate was observed in the reaction. The solid acid catalyst could be recovered easily by filtration and the recovered catalyst was reusable in the same reactions without a significant loss of catalytic activity.

Polymer-supported PPh3 as a reusable organocatalyst for the Mukaiyama aldol and Mannich reaction

An easily accessible and user-friendly polymer-supported phosphine PS-PPh3 catalyzes the aldol reaction of aldehydes and imines. A broad range of aldehydes and imines could be applied under mild conditions using 5-10 mol% PS-PPh3. PS-PPh3 was easily recovered and reused with minimal loss of activity. This journal is the Partner Organisations 2014.

Recognition of aromatic compounds by π pocket within a cage-shaped borate catalyst

Taking shape: The ability of a Lewis acid catalyst to distinguish between aromatic and aliphatic hydrocarbon moieties was accomplished by using cage-shaped borate catalysts B(OC6H3Aryl)3CH (see picture) having a π pocket derived from aryl substituents surrounding the boron center. The catalyst predominantly activated aromatic aldehydes over aliphatic ones for reaction. Copyright