144604-65-9Relevant academic research and scientific papers
Rationally Designed Chiral Synthons Enabling Asymmetric Z- and E-Selective Vinylogous Aldol Reactions of Aldehydes
Padarti, Akhil,Han, Hyunsoo
, p. 1448 - 1452 (2018)
In a conceptually different approach, highly stereoselective 2-oxonia-Cope rearrangement reactions between rationally designed nonracemic vinylogous aldolation synthons and aldehydes are described to provide δ-hydroxy-α,β-unsaturated esters with excellent
Synthesis of atorvastatin lactone linker constructs for target fishing
Sawant, Pramod,Maier, Martin E.
, p. 6576 - 6585 (2013/01/15)
With the aim of connecting atorvastatin lactone 9 to a linker for affinity-based target fishing, a concise route to the pyrrolecarboxylic acid 8 was developed. Key features of the synthesis of the diol-containing side-chain were a catalytic enantioselecti
Total synthesis of the ionophore antibiotic CP-61,405 (routiennocin)
Diez-Martin, David,Kotecha, Nikesh R.,Ley, Steven V.,Mantegani, Sergio,Menendez, J. Carlos,Organ, Helen M.,White, Andrew D.,Banks, Bernard J.
, p. 7899 - 7938 (2007/10/02)
The total synthesis of the spiroketal ionophore antibiotic routiennocin 1 (CP-61,405) employing π-allyltricarbonyl iron lactone complexes is described. These complexes were used as precursors for the preparation of substituted 2-phenylsulphonyl pyrans whi
