144688-72-2

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 2-cyano-2-(phenylmethyl)-, 1,1-dimethylethyl ester
• CAS NO: 144688-72-2
• Molecular Formula: C17H22N2O2
• Molecular Weight: 286.374
• Mol File: 144688-72-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 2-cyano-2-(phenylmethyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 2-cyano-2-(phenylmethyl)-, 1,1-dimethylethyl ester(144688-72-2)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 2-cyano-2-(phenylmethyl)-, 1,1-dimethylethyl ester(144688-72-2)

Safety Data

• Hazardous Substances Data: 144688-72-2(Hazardous Substances Data)

Upstream product

• 144688-69-7 tert-butyl 2-methoxypyrrolidine-1-carboxylate 
• 86953-79-9 tert-butyl pyrrolidine-1-carboxylate 
• 100-39-0 benzyl bromide 
• 144688-70-0 N-tert-butoxycarbonyl-α-cyanopyrrolidine 

Downstream Products

• 144688-81-3 α-benzyl-N-tert-butoxycarbonylpyrrolidine 

Relevant articles and documents

Electroorganic chemistry 139. Electroreductive decyanation of nitriles and its application to synthesis of α-alkylamines

Electroreduction of nitriles gave the corresponding decyanated products when Zn was used as the material of cathode in aprotic solvent (DMF or MeCN) containing Et4NOTs as a supporting electrolyte. Alkylation of amines at the α-position was effectively achieved by cyanation of amines at the α-position, and α-alkylation of the resultant α-amino nitriles followed by the electroreductive decyanation.