144735-56-8

Basic information

• Product Name: 5-((2-methoxycarbonyl)ethyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran

Upstream product

• 1486-53-9 4-(benzyloxy)-3-methoxybenzoic acid 
• 1486-52-8 3-methoxy-4-benzyloxybenzoyl chloride 
• 515814-05-8 2-[4-(benzyloxy)-3-methoxyphenyl]-5-bromo-7-methoxybenzofuran 
• 35090-64-3 2-hydroxy-3-methoxy-5-bromobenzyl alcohol 
• 5034-74-2 5-bromo-3-methoxysalicylaldehyde 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 144735-53-5 β-(3-methoxy-4-(benzyloxy)phenyl)-β-chloracrolein 
• 144735-54-6 1-ethynyl-4-(benzyloxy)-3-methoxybenzene 
• 61222-88-6 methyl 3-methoxy-4-hydroxy-5-bromocinnamate 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 121-33-5 vanillin 
• 1835-11-6 4-benzyloxy-3-methoxyacetophenone 
• 144735-55-7 5-(2-(methoxycarbonyl)trans-ethenyl)-7-methoxy-2-(3'-methoxy-4'-(benzyloxy)phenyl)benzofuran 

Downstream Products

• 144735-59-1 5-(2-(methoxycarbonyl)ethyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-3-carbaldehyde 
• 144735-57-9 2-(4-hydroxy-3-methoxyphenyl)-5-(3-hydroxypropyl)-7-methoxybenzofurane 
• 36307-23-0 5-(3-hydroxypropyl)-7-methoxy-3-methyl-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran 
• 135040-83-4 5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)-3-benzo[b]furan-carbaldehyde 
• 135040-88-9 2-(4-hydroxy-3-methoxyphenyl)-5-(3-acetoxypropyl)-7-methoxybenzofuran 
• 135040-90-3 5-(3-acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-3-carbaldehyde 
• 135040-89-0 5-(3-acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-4-carbaldehyde 
• 144735-70-6 3-acetyl-5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran 
• 144735-77-3 5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-4-carbaldehyde 
• 70610-22-9 2-(3-methoxy-4-hydroxyphenyl)-3-methoxycarbonyl-5-(3-hydroxypropyl)-7-methoxybenzo[b]furan 
• 144735-76-2 3-cyano-5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran 
• 144735-60-4 5-(2-carboxyethyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-3-carbaldehyde 
• 144735-69-3 4-acetyl-5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran 
• 144735-66-0 4-bromo-5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-3-carbaldehyde 

Relevant articles and documents

An alternate method for the synthesis of 2-aryl/alkyl-5-bromo-7-methoxy benzofurans; application to the synthesis of Egonol, Homoegonol, and analogs via Heck reaction

We herein report the general, versatile, and convenient method for the synthesis of 2-arly/alkyl-5-bromo-7-methoxy benzofurans from easily available o-Vanillin in five steps. These benzofurans was successfully converted into biological active natural products Egonol, Homoegonol, and analogous on applying Heck reaction using ethyl/methyl acrylate in the presence of palladium catalyst.