1448812-37-0

Basic information

• Product Name: C₂₂H₂₃ClN₄O₄
• CAS NO: 1448812-37-0
• Molecular Weight: 442.902
• Mol File: 1448812-37-0.mol

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₃ClN₄O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₃ClN₄O₄(1448812-37-0)
• EPA Substance Registry System: C₂₂H₂₃ClN₄O₄(1448812-37-0)

Safety Data

• Hazardous Substances Data: 1448812-37-0(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 221291-87-8 N-(3-chloro-2-hydroxyphenyl)propionamide 
• 603-86-1 2-chloro-6-nitrophenol 
• 897765-83-2 C₁₂H₁₃N₃O₂ 
• 1448812-08-5 N-(3-chloro-5-formyl-2-hydroxyphenyl)propionamide 
• 64845-28-9 methyl 2-cyano-3-ethoxy-2-butenoate 

Relevant articles and documents

Structure-activity relationship study of phenylpyrazole derivatives as a novel class of anti-HIV agents

The structure-activity relationship of phenylpyrazole derivative 1 was investigated for the development of novel anti-HIV agents. Initial efforts revealed that the diazenyl group can be replaced by an aminomethylene group. In addition, we synthesized various derivatives by the reductive amination of benzaldehydes with 5-aminopyrazoles and carried out parallel structural optimization on the benzyl group and the pyrazole ring. This optimization led to a six-fold more potent derivative 32j than the lead compound 1, and this derivative has a 3′,4′-dichloro-(1,1′-biphenyl)-3-yl group.