1449295-90-2

Basic information

• Product Name: C₂₉H₁₈O₅
• Synonyms: C₂₉H₁₈O₅
• CAS NO: 1449295-90-2
• Molecular Weight: 446.459
• Mol File: 1449295-90-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₉H₁₈O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₁₈O₅(1449295-90-2)
• EPA Substance Registry System: C₂₉H₁₈O₅(1449295-90-2)

Safety Data

• Hazardous Substances Data: 1449295-90-2(Hazardous Substances Data)

Upstream product

• 52927-22-7 6-cyano-2-naphthol 
• 16712-64-4 6-Hydroxy-2-naphthoic acid 
• 100-52-7 benzaldehyde 
• 15231-91-1 6-bromo-naphthalen-2-ol 
• 135-19-3 β-naphthol 

Downstream Products

• 1449295-93-5 C₃₃H₂₈N₂O₅ 
• 1449295-95-7 14-phenyl-14H-dibenzo[a,j]xanthene-3,11-dimethanol 
• 1449295-99-1 C₃₃H₃₂N₂O₃ 

Relevant articles and documents

Synthesis and cytotoxicity of n-substituted dibenzo[a,j]xanthene-3,11-dicarboxamide derivatives

In order to study the structure-activity relationships of xanthene derivatives, four series of N-substituted 14-aryl-14H-dibenzo[a,j]xanthene-3,11-dicarboxamide derivatives were synthesized. The structures of all compounds were identified by 1H-NMR HR-MS and IR spectra in which compounds 6a-h were further identified by 13C-NMR spectra. The in vitro antitumor activity of the synthesized compounds was tested by MTT assay. Most of them displayed strong inhibitory activity on human hepatocellular carcinoma cell lines (SK-HEP-1 HepG2 and SMMC-7721 cells) and acute promyelocytic leukemia NB4 cells. Compounds 6c-6e exhibited significant inhibitory activity against NB4 cells with IC50 values of 0.52 μM and 0.76 μM respectively much lower than 5.31 μM of the positive control As2O3.