1450-85-7

Usage

Uses

Used in Chemical Synthesis:
2-Mercaptopyrimidine is used as a reagent for the highly selective palladium-catalyzed kinetic resolutions of racemic cyclic allylic carbonates and racemic acyclic allylic carbonates. Its unique chemical properties allow for the efficient synthesis of specific enantiomers, which are crucial in the development of chiral drugs and pharmaceuticals.
Used in Environmental Science:
2-Mercaptopyrimidine is used as a model compound to study the photodegradation process in aerated aqueous solutions, particularly when using zinc oxide as a catalyst. This application helps in understanding the behavior of similar compounds in the environment and their potential impact on water quality and ecosystems.
Used in Pharmaceutical Research:
Although not explicitly mentioned in the provided materials, 2-Mercaptopyrimidine's unique structure and chemical properties make it a potential candidate for further research in the development of new drugs and therapeutic agents, particularly in the fields of oncology and other medical applications where pyrimidine-based compounds have shown promise.

InChI:InChI=1/C4H4N2S/c7-4-5-2-1-3-6-4/h1-3H,(H,5,6,7)

Upstream product

• 1722-12-9 2-chloropyrimidine 
• 17356-08-0 thiourea 
• 122-31-6 malondialdehyde bis(diethyl acetal) 
• 34899-98-4 (E)-3-(diethylamino)acrylaldehyde 
• 10348-83-1 3t-phenoxy-acrylaldehyde 
• 84358-82-7 2-(tert-butylthio)pyrimidine 
• 15718-46-4 2,2'-dipyrimidyl disulfide 
• 102-52-3 malonaldehydebis(dimethylacetal) 
• 598-52-7 1-(methyl)-thiourea 

Downstream Products

• 88768-45-0 2-(carboxymethylthio)pyrimidine 
• 823-09-6 2-(methylsulfanyl)pyrimidine 
• 142047-90-3 pyrimidine-2-sulfonamide 
• 66702-61-2 2-(4-chloro-phenyl)-3-oxo-2,3-dihydro-thiazolo[3,2-a]pyrimidinylium betaine 
• 80815-02-7 C₁₂H₇N₃O₃S 
• 3739-82-0 2-ethoxy-pyrimidine 
• 43091-22-1 2-phenylthiazolo<3.2-a>pyrimidinium 3-oxide 
• 116457-85-3 1-((1,3-bis(benzyloxy)-2-propoxy)methyl)-2-thiopyrimidine 
• 289-95-2 PYRIMIDINE 
• 15718-46-4 2,2'-dipyrimidyl disulfide 
• 10132-25-9 2-(ethylsulfanyl)pyrimidine 
• 83335-28-8 2-pyrimidinyl vinyl sulfide 
• 7431-45-0 2-phenylpyrimidine 
• 152759-57-4 Cu(P(C₆H₅)3)2(C₄H₄N₂S)I 

Relevant academic research and scientific papers

Spectroscopic and computational investigation of the ground and low excited states of some symmetrical heterocyclic disulfides

The electronic absorption and emission spectra of some symmetrical heterocyclic disulfides are investigated. The reversible disulfide - thione transformation in water is discussed in view of the complex equilibrium processes present. UV irradiation and pH influence on the above transformation is also studied. The emission properties at room and low temperature are related to the computed molecular geometries of the ground and low excited states of the compounds.

Topical compositions comprising protected functional thiols

This invention relates to a topical composition for treating amino acid based substrates comprising a protected thiol compound having the formula R—(S—Pr)m where R is a functional group, S is sulfur, and Pr is a heterocyclic protecting group, and m is an integer between 1 and 100. The invention further relates to systems which comprise this protected thiol compound and an activating mechanism. The protected thiol compounds of the present invention may be used in hair care compositions, textile care compositions, cosmetic compositions, oral care compositions, skin care, nail care, laundry care, acne care and animal care compositions. Preferred embodiments of the present invention provide a modified UV absorber and a modified antioxidant, methods for making them and compositions conprising them.

Topical compositions comprising protected functional thiols

This invention relates to a topical composition for treating amino acid based substrates comprising a protected thiol compound having the formula R—(S—Pr) m where R is a functional group, S is sulfur, and Pr is a heterocyclic protecting group, and m is an integer between 1 and 100. The invention further relates to systems which comprise this protected thiol compound and an activating mechanism. The protected thiol compounds of the present invention may be used in hair care compositions, textile care compositions, cosmetic compositions, oral care compositions, skin care, nail care, laundry care, acne care and animal care compositions. Preferred embodiments of the present invention provide a modified UV absorber and a modified antioxidant, methods for making them and compositions conprising them.

Kinetics and mechanism of the formation and reactions of S-nitroso derivatives of some heterocyclic thiones

Rate and equilibrium measurements have been obtained for the nitrosation (using nitrous acid in dilute acid aqueous solution) of the following thione-thiol nitrogen heterocyclic species and for the decomposition reactions of the formed S-NO- io

Thione-Disulfide Interchange of some Heterocyclic Tautomeric Thiones and their Symmetrical Bisulfides

The UV/Vis spectroscopic properties of some symmetrical disulfides derived from potentially tautomeric thiones are investigated. Reversed thione-disulfide transformation is observed, and the influence of several factors including the nature of solvent, concentration, and UV irradiation, is studied. Possible implication of the tautomeric thiol form and the importance of this thione-disulfide redox system in biological aspects is suggested. A general scheme including monomer-dimer equilibrium, thione-thiol tautomeric equilibrium, and reversible thiol-disulfide redox behaviour is proposed in order to explain the factors affecting the overall thione-disulfide transformation.

Artificial DNA base pair analogues

The present invention is directed to new artificial base pairs comprising complementary artificial purines and pyrimidines and methods of using artificial complementary base pairs.

INTRODUCTION OF SULFUR IN COMPOUNDS WITH REACTIVE HALOGEN ATOMS VIA THE t-BUTYLTHIOLATE ANION

The preparation of t-butylthioethers from examples of halogen substituted heterocycles are described.S-Dealkylation of the t-butylthioethers readily takes place by pyrolyses with catalytic amounts of aluminum chloride or p-toluenesulfonic acid.