1450909-69-9Relevant academic research and scientific papers
Light promoted aqueous phase amine synthesis via three-component coupling reactions
Zhang, Lina,Deng, Youquan,Shi, Feng
, p. 5217 - 5219 (2013)
By applying a simple TiO2-(NH4)2S 2O8 system and promoted by UV light, the three-component reactions of cyclic ether, aniline and aldehyde can be progressed efficiently. 29 substituted amines with different structures were synthesized with up to 97% isolated yields. Isotope effect study revealed that the rate-determining step might be the nucleophilic addition step but not radical generation.
