145104-31-0

Upstream product

• 118-90-1 ortho-methylbenzoic acid 
• 2728-04-3 N,N-diethyl-ortho-toluamide 
• 933-88-0 ortho-toluoyl chloride 
• 145104-23-0 ortho-trimethylsilylmethyl-N-methylbenzamide 
• 54463-74-0 3-(2-methylphenyl)-1,2-dihydroisoquinolin-1-one 
• 74-88-4 methyl iodide 
• 145104-25-2 2,N-Dimethyl-N-(2-trimethylsilanylmethyl-benzoyl)-benzamide 

Downstream Products

• 244128-26-5 4-bromo-3-<2-(dibromomethyl)phenyl>-2-methyl-1(2H)-isoquinolinone 
• 244128-27-6 2-(4-bromo-2-methyl-1-oxo-1,2-dihydro-3-isoquinolinyl)benzaldehyde 
• 244128-28-7 4-bromo-2-methyl-3-(2-vinylphenyl)-1(2H)-isoquinolinone 
• 244128-29-8 4-bromo-3-<2-(2,2-dimethoxyethyl)phenyl>-2-methyl-isoquinolinone 
• 1352287-38-7 4-hydroxymethyl-2-methyl-3-o-tolyl-2H-isoquinolin-1-one 
• 1352287-74-1 4-ethoxymethyl-2-methyl-3-o-tolyl-2H-isoquinolin-1-one 
• 1352287-77-4 4-isobutoxymethyl-2-methyl-3-o-tolyl-2H-isoquinolin-1-one 
• 1352287-93-4 4-(2-isopropyl-phenoxymethyl)-2-methyl-3-o-tolyl-2H-isoquinolin-1-one 
• 1352287-94-5 4-(2-methoxy-4-methyl-phenoxymethyl)-2-methyl-3-o-tolyl-2H-isoquinolin-1-one 
• 1352287-24-1 2-methyl-1-oxo-3-o-tolyl-1,2-dihydro-isoquinoline-4-carbaldehyde 

Relevant academic research and scientific papers

A novel synthesis of benzo[c]phenanthridine skeleton and biological evaluation of isoquinoline derivatives

Benzo[c]phenanthridine skeleton was synthesized from easily available starting N-methyl-o-toluamide 2 and o-methylbenzonitrile 5 in 7 steps. Radical cyclization of styrene 10 afforded 6,11-dimethyl-6,11-dihydro-5H- indeno[1,2-c]isoquinolin-5-one 13. Most

Synthesis of 12-oxobenzo[c]phenanthridinones and 4-substituted 3-arylisoquinolones via Vilsmeier-Haack reaction

Vilsmeier-Haack reaction on 3-arylisoquinolones resulted in versatile 4-formylated 3-arylisoquinolones that were further derivatized into 12-oxobenzo[c]phenanthridinones, 4-alkoxymethyl-3-arylisoquinolones, 3-aryl-4-phenoxymethylisoquinolones, 4-aminometh

Intramolecular Peterson olefination of ortho-trimethylsilylmethyl-N-acyl-N-alkylbenzamides. A new route to 2-alkyl-1(2H)isoquinolones

A variety of 2-alkyl-1(2H)isoquinolones has been efficiently synthesized by intramolecular Peterson olefination of ortho-trimethylsilylmethyl-N-acyl-N-alkylbenzamides.