A novel synthesis of benzo[c]phenanthridine skeleton and biological evaluation of isoquinoline derivatives

DOI: 10.1248/cpb.47.900

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 900 - 902 (1999)

Update date:2022-08-03

Topics:

Authors:

Cho, Won-Jea

Park, Myun-Ji

Imanishi, Takeshi

Chung, Byung-Ho

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Article abstract of DOI:10.1248/cpb.47.900

Benzo[c]phenanthridine skeleton was synthesized from easily available starting N-methyl-o-toluamide 2 and o-methylbenzonitrile 5 in 7 steps. Radical cyclization of styrene 10 afforded 6,11-dimethyl-6,11-dihydro-5H- indeno[1,2-c]isoquinolin-5-one 13. Most

Full text of DOI:10.1248/cpb.47.900

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