244128-27-6Relevant articles and documents
Design, docking, and synthesis of novel indeno[1,2-c]isoquinolines for the development of antitumor agents as topoisomerase I inhibitors
Cho, Won-Jea,Le, Quynh Manh,My Van, Hue Thi,Youl Lee, Kwang,Kang, Bok Yun,Lee, Eung-Seok,Lee, Sang Kook,Kwon, Youngjoo
, p. 3531 - 3534 (2008/02/07)
An intramolecular radical cyclization reaction of 4-bromo-3-arylisoquinolines 11a-c allowed the efficient synthesis of 11-methylindenoisoquinolines 2a-c. 5-(2-Aminoethylamino)indeno[1,2-c]isoquinolin-11-one 4 was also prepared in the convenient manner. Th
A novel synthesis of benzo[c]phenanthridine skeleton and biological evaluation of isoquinoline derivatives
Cho, Won-Jea,Park, Myun-Ji,Imanishi, Takeshi,Chung, Byung-Ho
, p. 900 - 902 (2007/10/03)
Benzo[c]phenanthridine skeleton was synthesized from easily available starting N-methyl-o-toluamide 2 and o-methylbenzonitrile 5 in 7 steps. Radical cyclization of styrene 10 afforded 6,11-dimethyl-6,11-dihydro-5H- indeno[1,2-c]isoquinolin-5-one 13. Most