145149-86-6Relevant articles and documents
HEPARANASE INHIBITORS FOR TREATMENT OF DIABETES
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, (2021/07/10)
Anti-heparanase compounds for the treatment of diabetes are described. The anti-heparanase compounds are high affinity, synthetic glycopolymers that result in minimal anticoagulant activity. Stereoselective fluorinated forms of these compounds are also pr
Phenanthroline-Catalyzed Stereoretentive Glycosylations
Yu, Fei,Li, Jiayi,DeMent, Paul M.,Tu, Yi-Jung,Schlegel, H. Bernhard,Nguyen, Hien M.
, p. 6957 - 6961 (2019/04/17)
Carbohydrates are essential moieties of many bioactive molecules in nature. However, efforts to elucidate their modes of action are often impeded by limitations in synthetic access to well-defined oligosaccharides. Most of the current methods rely on the
Solution-Phase Hexasaccharide Synthesis Using Glucosyl Iodides
Lam, Son N.,Gervay-Hague, Jacquelyn
, p. 2039 - 2042 (2007/10/03)
(Equation Presented) Oligosaccharides composed of 1,6-glucosyl residues have been prepared from glucosyl iodides. The reactions are highly stereoselective, giving the α-glycosides as the only isolated products in yields ranging from 84% to 94%. Oligomer s