14527-44-7

Basic information

• Product Name: Methyl 5-thiazolecarboxylate
• Synonyms: methyl 1,3-thiazole-5-carboxylate;METHYL 5-THIAZOLECARBOXYLATE;METHYL THIAZOLE-5-CARBOXYLATE;RARECHEM AL BF 1261;5-Thiazolecarboxylic acid, methyl ester;Thiazole-5-carboxylic acid methyl ester;Methyl 5-thiazolecar;NSC 321257
• CAS NO: 14527-44-7
• Molecular Formula: C₅H₅NO₂S
• Molecular Weight: 143.16
• Product Categories: blocks;Carboxes;Thiazoles;Building Blocks;C3 to C7;Chemical Synthesis;Heterocyclic Building Blocks;New Products for Chemical Synthesis
• Mol File: 14527-44-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 68-69°C
• Boiling Point: 87-90°C (10 mmHg)
• Flash Point: 86.8 °C
• Appearance: /
• Density: 1.45
• Vapor Pressure: 0.117mmHg at 25°C
• Refractive Index: 1.539
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 0.80±0.10(Predicted)
• CAS DataBase Reference: Methyl 5-thiazolecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-thiazolecarboxylate(14527-44-7)
• EPA Substance Registry System: Methyl 5-thiazolecarboxylate(14527-44-7)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 14527-44-7(Hazardous Substances Data)

Usage

General Description

Methyl 5-thiazolecarboxylate, also known as methyl thiazole-5-carboxylate, is a chemical compound with the molecular formula C6H5NO2S. It is a colorless to pale yellow liquid with a pungent odor, often used as a flavoring agent in the food and beverage industry. Methyl 5-thiazolecarboxylate is also utilized in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals due to its versatile reactivity and potential biological activity. It is known for its distinctive fruity, nutty, and meaty odor, making it a popular choice in the creation of various food flavors and fragrances. Additionally, this compound is considered to have low toxicity and is generally recognized as safe for use in food applications.

InChI:InChI=1/C5H5NO2S/c1-8-5(7)4-2-9-3-6-4/h2-3H,1H3

Upstream product

• 186581-53-3 diazomethane 
• 14527-41-4 thiazole-5-carboxylic acid 
• 6633-61-0 methyl 2-aminothiazole-5-carboxylate 
• 463-04-7 n-Amyl nitrite 
• 110-46-3 isopentyl nitrite 
• 20656-61-5 methyl 2-chloro-3-oxopropionate 
• 115-08-2 thiocarboxamide 

Downstream Products

• 38585-74-9 thiazol-5-yl-methanol 
• 1593701-07-5 methyl 2-(5-(4-methoxybenzyloxy)pyridin-2-yl)thiazole-5-carboxylate 
• 1261080-59-4 methyl 2-acetylthiazole-5-carboxylate 

Relevant articles and documents

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BROADSPECTRUM SUBSTITUTED BENZISOXAZOLE SULFONAMIDE HIV PROTEASE INHIBITORS

The present invention concerns the compounds having the formula N-oxides, salts, stereoisomeric forms, racemic mixtures, prodrugs esters and metabolites thereof.It further relates to their use as broadspectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. It also concerns combinations thereof with another anti-retroviral agent, and to their use in assays as reference compounds or as reagents.

ALPHA- AND BETA-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS

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