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1453499-18-7

1-(2-(4-((dimethylamino)methyl)-2-methylphenyl)-2-oxoethyl)-4-((5-fluoropyridin-2-yl)methoxy)pyridin-2(1H)-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1453499-18-7 Structure

  • Basic information

    1. Product Name: 1-(2-(4-((dimethylamino)methyl)-2-methylphenyl)-2-oxoethyl)-4-((5-fluoropyridin-2-yl)methoxy)pyridin-2(1H)-one
    2. Synonyms:
    3. CAS NO:1453499-18-7
    4. Molecular Formula:
    5. Molecular Weight: 409.46
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1453499-18-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(2-(4-((dimethylamino)methyl)-2-methylphenyl)-2-oxoethyl)-4-((5-fluoropyridin-2-yl)methoxy)pyridin-2(1H)-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(2-(4-((dimethylamino)methyl)-2-methylphenyl)-2-oxoethyl)-4-((5-fluoropyridin-2-yl)methoxy)pyridin-2(1H)-one(1453499-18-7)
    11. EPA Substance Registry System: 1-(2-(4-((dimethylamino)methyl)-2-methylphenyl)-2-oxoethyl)-4-((5-fluoropyridin-2-yl)methoxy)pyridin-2(1H)-one(1453499-18-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1453499-18-7(Hazardous Substances Data)

1453499-18-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1453499-18-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,3,4,9 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1453499-18:
(9*1)+(8*4)+(7*5)+(6*3)+(5*4)+(4*9)+(3*9)+(2*1)+(1*8)=187
187 % 10 = 7
So 1453499-18-7 is a valid CAS Registry Number.

1453499-18-7Downstream Products

1453499-18-7Relevant articles and documents

Design, synthesis and evaluation of MCH receptor 1 antagonists - Part III: Discovery of pre-clinical development candidate BI 186908

Oost, Thorsten,Heckel, Armin,Kley, J?rg T.,Lehmann, Thorsten,Müller, Stephan,Roth, Gerald J.,Rudolf, Klaus,Arndt, Kirsten,Budzinski, Ralph,Lenter, Martin,Lotz, Ralf R.H.,Maier, Gerd-Michael,Markert, Michael,Thomas, Leo,Stenkamp, Dirk

, p. 3275 - 3280 (2015/07/08)

Abstract Although overweight and obesity are highly prevalent conditions, options to treat them are still very limited. As part of our search for safe and effective MCH-R1 antagonists for the treatment of obesity, two series of pyridones and pyridazinones

NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

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Paragraph 0305, (2013/09/26)

The present invention relates to compounds of general formula I, wherein the groups R1, R2, L1, L2, U and B are as defined in the application, which have valuable pharmacological properties, and in particular modulate the activity of the MCH receptor.

PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS MCH - RECEPTOR MODULATORS

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Page/Page column 59, (2013/09/26)

The present invention relates to compounds of general formula I, wherein the groups R1, R2, L1, L2, U and B are as defined in the application, which have valuable pharmacological properties, and in particular modulate the activity of the MCH receptor.

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