145354-39-8

Basic information

• Product Name: 1α-[(tert-butyldimethylsilyl)oxy]-25-[(methoxymethyl)oxy]previtamin D₂ tert-butyldimethylsilyl ether
• Synonyms: 1α-[(tert-butyldimethylsilyl)oxy]-25-[(methoxymethyl)oxy]previtamin D₂ tert-butyldimethylsilyl ether
• CAS NO: 145354-39-8
• Molecular Weight: 701.234
• Mol File: 145354-39-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1α-[(tert-butyldimethylsilyl)oxy]-25-[(methoxymethyl)oxy]previtamin D₂ tert-butyldimethylsilyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 1α-[(tert-butyldimethylsilyl)oxy]-25-[(methoxymethyl)oxy]previtamin D₂ tert-butyldimethylsilyl ether(145354-39-8)
• EPA Substance Registry System: 1α-[(tert-butyldimethylsilyl)oxy]-25-[(methoxymethyl)oxy]previtamin D₂ tert-butyldimethylsilyl ether(145354-39-8)

Safety Data

• Hazardous Substances Data: 145354-39-8(Hazardous Substances Data)

Upstream product

• 145354-33-2 (22R)-des-A,B-8β-(benzoyloxy)-22<<(1'R)-2'-carboxy-1'-methylethyl>oxy>-23-cholestyn-25-ol 
• 145354-29-6 (20S)-des-A,B-8β-(benzoyloxy)-20-<(2'R,6'R)-6'-methyl-4'-oxo-1',3'-dioxan-2'-yl>pregnane 
• 145354-35-4 (22R)-des-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>-22-<<(1'R)-3'-oxo-3'-<(methoxymethyl)oxy>-1'-methylpropyl>-oxy>cholest-23-yne 
• 145354-36-5 (22E,24S)-des-A,B-25-<(methoxymethyl)oxy>-8,22-ergostadien-8-yl Trifluoromethanesulfonate 
• 100858-20-6 (22R)-des-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-ol 
• 100858-26-2 (22E,24S)-de-A,B-25-<(methoxymethyl)oxy>ergost-22-en-8-one 
• 55812-82-3 (1R,3aR,4S,7aR)-7a-methyl-1-<(2E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl>-octahydro-1H-inden-4-ol 
• 68702-86-3 (24R,22E)-des-A,B-8β-(benzoyloxy)ergost-22-ene 
• 66774-71-8 Benzoic acid (1R,3aR,4S,7aR)-7a-methyl-1-((S)-1-methyl-2-oxo-ethyl)-octahydro-inden-4-yl ester 
• 170207-97-3 (E)-(2S,3S)-2-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-6-methoxymethoxy-6-methyl-hept-4-en-3-ol 
• 169951-01-3 Phosphoric acid (E)-(S)-1-{(S)-1-[(1R,3aR,4S,7aR)-4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-ethyl}-4-methoxymethoxy-4-methyl-pent-2-enyl ester diethyl ester 
• 194158-66-2 Phosphoric acid diethyl ester (E)-(S)-4-methoxymethoxy-4-methyl-1-[(S)-1-((1R,3aR,7aR)-7a-methyl-4-oxo-octahydro-inden-1-yl)-ethyl]-pent-2-enyl ester 
• 194158-92-4 Phosphoric acid diethyl ester (E)-(S)-1-[(S)-1-((1R,3aR,4S,7aR)-4-hydroxy-7a-methyl-octahydro-inden-1-yl)-ethyl]-4-methoxymethoxy-4-methyl-pent-2-enyl ester 
• 104651-47-0 (S)-2-[(1R,3aR,4S,7aR)-octahydro-4-[(1,1-dimethylethyl)dimethylsilyloxy]-7a-methyl-1H-inden-1-yl]propanal 

Downstream Products

• 60133-18-8 ercalcitriol 

Relevant articles and documents

A Short, Efficient Copper-Mediated Synthesis of 1α,25-Dihydroxyvitamin D2 (1α,25-Dihydroxyergocalciferol) and C-24 Analogs

Two synthetic routes to the nonnatural hormone 1α,25-dihydroxyergocalciferol [2b, 1α,25-(OH)2D2] and analogs modified at C-24 have been developed both starting from aldehyde 7b. Key steps in route A (eight steps, ≈38% overall yield f