145485-86-5Relevant academic research and scientific papers
Benzolactam growth hormone secretagogues: Replacement of the C-3 amide bond in L-692,429
Ok, Hyun O.,Szumiloski, John L.,Doldouras, George A.,Schoen, William R.,Cheng, Kang,Chan, Wanda W.-S.,Butler, Bridget S.,Smith, Roy G.,Fisher, Michael H.,Wyvratt, Matthew J.
, p. 3051 - 3056 (1996)
The synthesis and structure-activity relationships of various C-3 amide bond modifications in the novel nonpeptidyl growth hormone secretagogue L-692,429 are described. Several C-3 amide surrogates were prepared and the urea moiety was found to exhibit growth hormone releasing activity similar to that observed with L-692,429.
