1455094-75-3

Upstream product

• 1455094-73-1 3-[(4-hydroxy-1-iodo-2-oxy-7-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid ethyl ester 
• 1455091-04-9 2-(chloromethyl)-4-phenoxybenzoic acid methyl ester 
• 1572-98-1 2-cyano-2-methyl-propionic acid ethyl ester 
• 59193-77-0 3-amino-2,2-dimethylpropionic acid ethyl ester 
• 1455091-06-1 2-{[(methoxycarbonylmethyl)(toluene-4-sulfonyl)amino]methyl}-4-phenoxybenzoic acid methyl ester 
• 1455091-10-7 4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid methyl ester 
• 64169-34-2 5-bromophthalide 
• 1455094-69-5 3-[(4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid ethyl ester 
• 1455094-71-9 3-[(4-hydroxy-2-oxy-7-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid ethyl ester 
• 108-95-2 phenol 
• 57830-14-5 5-phenoxy-3H-isobenzofuran-1-one 

Downstream Products

• 1455090-30-8 3-[(1-cyano-4-hydroxy-2-oxy-7-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid 

Relevant academic research and scientific papers

4 -HYDROXY- ISOQUINOLINE COMPOUNDS AS HIF HYDROXYLASE INHIBITORS

The present invention relates to novel compounds of formula (I), and compositions capable of inhibiting PHD1 enzyme activity selectively over other isoforms, for example, PHD2 and/or PHD3 enzymes. The invention also relates to compounds of formula (I) for use in disorders such as muscle degeneration, colitis, IBD, and certain ischemias.