145618-70-8Relevant articles and documents
New α,β-Didehydroamino Acid Derivatives as Precursors in the Synthesis of 1-Aminocyclopropanecarboxylic Acids
Cativiela, Carlos,Diaz-de-Villegas, Maria D.,Jimenez, Ana I.
, p. 9157 - 9166 (1994)
The reaction of N-(diphenylmethylene)didehydroalanine methyl ester and N-didehydroalanine methyl ester with diazoalkanes or ylides gives the corresponding cyclopropane derivatives in high yields.The cis/trans ratio of these compounds was dependent on substrate, reagent and reaction temperature.From stereochemically homogeneous compounds the corresponding 1-aminocyclopropanecarboxylic acids were easily obtained by acid hydrolysis.
New efficient synthesis of 1-aminocyclopropanecarboxylic acid (ACC)
Cativiela,Diaz-de-Villegas,Jimenez
, p. 2955 - 2963 (2007/10/02)
A new efficient synthesis of 1-aminocyclopropanecarboxylic acid (ACC) from methyl 2-diphenylmethyleneaminoacrylate in nearly quantitatie yield has been deeloped. The key step in the synthesis is the remoal of both protecting groups in mild conditions and
