72784-43-1

Basic information

• Product Name: Methyl 1-Aminocyclopropanecarboxylate
• Synonyms: Methyl 1-Aminocyclopropanecarboxylate;Methyl 1-aminocyclopropane-1-carboxylate;ACPCM;Methyl 1-amino-1-cyclopropylcarboxylate;Cyclopropanecarboxylic acid, 1-aMino-, Methyl ester
• CAS NO: 72784-43-1
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115.13
• Product Categories: Amino Acids and Derivatives
• Mol File: 72784-43-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 136℃
• Flash Point: 12℃
• Appearance: /
• Density: 1.188
• Vapor Pressure: 7.4mmHg at 25°C
• Refractive Index: 1.494
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 6.01±0.20(Predicted)
• CAS DataBase Reference: Methyl 1-Aminocyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 1-Aminocyclopropanecarboxylate(72784-43-1)
• EPA Substance Registry System: Methyl 1-Aminocyclopropanecarboxylate(72784-43-1)

Safety Data

• Hazardous Substances Data: 72784-43-1(Hazardous Substances Data)

Usage

General Description

Methyl 1-aminocyclopropanecarboxylate, also known as ACCM or ACC methyl ester, is a chemical compound that is derived from the natural plant growth regulator, 1-aminocyclopropanecarboxylic acid (ACC). It is commonly used in research and agricultural applications as a precursor for the synthesis of ACC, which plays a crucial role in the regulation of ethylene biosynthesis, a hormone that regulates plant growth and development. Methyl 1-aminocyclopropanecarboxylate is a white crystalline solid that is soluble in water and is stable under normal conditions. Its ability to mimic the effects of ACC makes it a valuable tool for studying the physiological and biochemical processes related to plant growth and stress responses.

InChI:InChI=1/C5H9NO2/c1-8-4(7)5(6)2-3-5/h2-3,6H2,1H3

Upstream product

• 914223-82-8 (9H-fluoren-9-yl)methyl 1-(methoxycarbonyl)-cyclopropylcarbamate 
• 145618-70-8 1-(Benzhydrylidene-amino)-cyclopropanecarboxylic acid methyl ester 
• 72784-42-0 methyl 1-aminocyclopropane-1-carboxylate hydrochloride 
• 67-56-1 methanol 
• 22059-21-8 aminocyclopropane-1-carboxylic acid 

Downstream Products

• 33689-29-1 1-hydroxy-cyclopropanecarboxylic acid methyl ester 
• 96-20-8 2-aminobutanol 
• 74-85-1 ethene 
• 1260155-60-9 C₂₁H₂₄N₄O₃ 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE

Heterocyclic compounds are described that are lysophosphatidic acid receptor ligands that are useful in the treatment of lysophosphatidic acid receptor-dependent diseases and conditions, including but not limited to diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma; inflammatory diseases such as diabetic nephropathy and inflammatory bowel disease; ocular diseases such as diseases involving retinal degeneration; nerve diseases such as pruritus and pain. Non-limiting examples of those compounds include (RS)-3-Cyclopropyl-2-{4-[3-methyl-4((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-benzyloxy}-propionic acid and (R)-1-(4′-{5-[1-(2-Chloro-phenyl)-ethoxycarbonylamino]-4-fluoro-pyrazol-1-yl}-2-fluoro-biphenyl-4-yl)-cyclopropanecarboxylic acid.

Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes: 1. Identification of 1-amino-1-cycloalkyl carboxylic acid headgroups

Optimization of the amino acid residue within a series of anthranilimide-based glycogen phosphorylase inhibitors is described. These studies culminated in the identification of anthranilimides 16 and 22 which displayed potent in vitro inhibition of GPa in

Potential anti-inflammatory actions of the elmiric (lipoamino) acids

A library of amino acid-fatty acid conjugates (elmiric acids) was synthesized and evaluated for activity as potential anti-inflammatory agents. The compounds were tested in vitro for their effects on cell proliferation and prostaglandin production, and compared with their effects on in vivo models of inflammation. LPS stimulated RAW 267.4 mouse macrophage cells were the in vitro model and phorbol ester-induced mouse ear edema served as the principal in vivo model. The prostaglandin responses were found to be strongly dependent on the nature of the fatty acid part of the molecule. Polyunsaturated acid conjugates produced a marked increase in media levels of i15-deoxy-PGJ2 with minimal effects on PGE production. It is reported in the literature that prostaglandin ratios in which the J series predominates over the E series promote the resolution of inflammatory conditions. Several of the elmiric acids tested here produced such favorable ratios suggesting that their potential anti-inflammatory activity occurs via a novel mechanism of action. The ear edema assay results were generally in agreement with the prostaglandin assay findings indicating a connection between them.