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14580-01-9

14580-01-9

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14580-01-9 Usage

General Description

4-OXO-4-(2-PHENYLHYDRAZINO)BUTANOIC ACID is an organic compound consisting of a butanoic acid core with a phenylhydrazino group and a ketone functional group. It is a synthetic chemical that is not naturally occurring and is commonly used in research and chemical synthesis. The compound may have potential applications in pharmaceuticals or as a building block for other organic compounds. Its specific properties and potential uses would depend on further research and testing.

Check Digit Verification of cas no

The CAS Registry Mumber 14580-01-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,5,8 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 14580-01:
(7*1)+(6*4)+(5*5)+(4*8)+(3*0)+(2*0)+(1*1)=89
89 % 10 = 9
So 14580-01-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N2O3/c13-9(6-7-10(14)15)12-11-8-4-2-1-3-5-8/h1-5,11H,6-7H2,(H,12,13)(H,14,15)

14580-01-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-oxo-4-(2-phenylhydrazinyl)butanoic acid

1.2 Other means of identification

Product number -
Other names succinic acid mono-(N'-phenyl-hydrazide)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14580-01-9 SDS

14580-01-9Relevant articles and documents

Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases

Rose, Nathan R.,Woon, Esther C. Y.,Tumber, Anthony,Walport, Louise J.,Chowdhury, Rasheduzzaman,Li, Xuan Shirley,King, Oliver N. F.,Lejeune, Clarisse,Ng, Stanley S.,Krojer, Tobias,Chan, Mun Chiang,Rydzik, Anna M.,Hopkinson, Richard J.,Che, Ka Hing,Daniel, Michelle,Strain-Damerell, Claire,Gileadi, Carina,Kochan, Grazyna,Leung, Ivanhoe K. H.,Dunford, James,Yeoh, Kar Kheng,Ratcliffe, Peter J.,Burgess-Brown, Nicola,Von Delft, Frank,Muller, Susanne,Marsden, Brian,Brennan, Paul E.,McDonough, Michael A.,Oppermann, Udo,Klose, Robert J.,Schofield, Christopher J.,Kawamura, Akane

supporting information; experimental part, p. 6639 - 6643 (2012/09/22)

The JmjC oxygenases catalyze the N-demethylation of Nε- methyl lysine residues in histones and are current therapeutic targets. A set of human 2-oxoglutarate analogues were screened using a unified assay platform for JmjC demethylases and related oxygenases. Results led to the finding that daminozide (N-(dimethylamino)succinamic acid, 160 Da), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily. Kinetic and crystallographic studies reveal that daminozide chelates the active site metal via its hydrazide carbonyl and dimethylamino groups.

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