145834-67-9

Upstream product

• 52334-81-3 2-chloro-5-trifluoromethylpyridine 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 99-91-2 para-chloroacetophenone 
• 69045-82-5 2-fluoro-5-(trifluoromethyl)pyridine 
• 50488-42-1 2-bromo-5-(trifluoromethyl)pyridine 

Downstream Products

• 372122-66-2 1-(4-fluorophenyl)-2-(2-(5-trifluoromethyl)pyridyl)ethanone oxime 
• 372122-55-9 2-(4-fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine 
• 401816-45-3 3-(4-fluorophenyl)-2-(2-(5-trifluoromethyl)pyridyl)-2H-azirine 
• 401816-46-4 2-(4-fluorophenyl)-3-acetyl-6-trifluoromethylpyrazolo[1,5-a]pyridine 
• 401816-47-5 2-(4-fluorophenyl)-3-(3-(dimethylamino)-2-propenoyl)-6-trifluoromethylpyrazolo[1,5-a]pyridine 
• 401816-50-0 N-Cyclopropyl-4-[2-(4-fluorophenyl)-6-trifluoromethylpyrazolo[1,5-a]pyridin-3-yl]-2-pyrimidinamine 
• 401816-64-6 2-(4-fluoro-phenyl)-3-[2-(3-hydroxy-propylamino)-pyrimidin-4-yl]-pyrazolo[1,5-a]pyridine-6-carboxylic acid ethyl ester 
• 401816-63-5 3-{4-[2-(4-fluoro-phenyl)-6-triethoxymethyl-pyrazolo[1,5-a]pyridin-3-yl]-pyrimidin-2-ylamino}-propan-1-ol 
• 401816-55-5 4-[2-(4-fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]-N-(3-(4-methoxybenzyloxy)propyl)-2-pyrimidinamine 
• 145833-95-0 4,5-dihydro-3-(4-fluorophenyl)-N-(4-trifluoromethylphenyl)-4-(5-trifluoromethyl-2-pyridyl)-1H-pyrazole-1-carboxamide 
• 1621276-89-8 1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)-1-[1-[5-(trifluoromethyl)-2-pyridyl]cyclopropyl]ethanol 

Relevant academic research and scientific papers

NOVEL MICROBIOCIDES

Compounds of formula (I) wherein the other substituents MBG, HetAr, R1, R2, R and R4 are as defined in claim 1, and their use in compositions and methods for the control and/or prevention of microbial infection, particularly fungal infection, in plants and to processes for the preparation of these compounds.

SUBSTITUTED PYRAZOLO [1,5-α] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE

The present invention is directed to substituted pyrazolo[l,5-α]pyridines and related methods for their synthesis and use.

Pyrazolo[1,5-a]pyridines as p38 kinase inhibitors

(Chemical Equation Presented) A convergent synthesis of substituted pyrazolo[1,5-a]pyridines has been achieved either via a regioselective [3 + 2] cycloaddition of N-aminopyridines with alkynes or by thermal cyclization of disubstituted azirines. Subseque

Process optimization and synthesis of 3-(4-fluorophenyl)-4,5-dihydro-N-[4-(trifluoromethyl)phenyl]-4-[5- (trifluoromethyl)-2-pyridyl]-1H-pyrazole-1-carboxamide

A convenient, high-yielding synthesis of the insecticide 3-(4-fluorophenyl)-4,5-dihydro-N-[4-(trifluoromethyl)phenyl]-4-[5- (trifluoromethyl)-2-pyridyl]-1H-pyrazole-1-carboxamide is presented. Attempted methenylation of the 2-pyridylacetophenone, obtained

3,4-disubstituted-4,5-dihydro-1H-pyrazoles and a method of preparation

3,4-Diaryl-4,5-dihydro-1H-pyrazole compounds having a selected 5- or 6-membered aromatic heterocyclic moiety in the 4-position and an optionally substituted phenyl moiety in the 3-position, such as 4,5-dihydro-3-(4-fluorophenyl)-4-(5-trifluoromethyl-2-pyr

3,4,N-trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides

3,4,N-triaryl-4,5-dihydro-1H-pyrazole-1-carboxamide compounds having an aryl moiety in the 4-position that is an optionally substituted pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, or quinolinyl moiety and aryl moieties in the 3-position and the N-position that are optionally substituted phenyl, pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, or quinolinyl moieties, such as N-(4-chlorophenyl)-4,5- -dihydro-3-(4-fluorophenyl)-4-(5-trifluoromethyl-2- -pyridinyl)-1H-pyrazole-1-carboxamide, were prepared and found to possess insecticidal utility. 1,2-Diarylethanone compounds were converted to 1,2-diaryl-2-propen-1-one compounds by treatment with bis(dimethylamino)methane, the 1,2-diaryl-2-propen-1-one compounds were converted to 3,4-diaryl-4,5-dihydro-1H-pyrazole compounds by treatment with hydrazine, and the 3,4-diaryl-4,5-dihydro-1H-pyrazole compounds were converted to the insecticidal subject compounds by treatment with an aryl isocyanate.