372122-66-2

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 52334-81-3 2-chloro-5-trifluoromethylpyridine 
• 145834-67-9 1-(4-fluorophenyl)-2-[5-(trifluoromethyl)-2-pyridyl]ethanone 

Downstream Products

• 401816-55-5 4-[2-(4-fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]-N-(3-(4-methoxybenzyloxy)propyl)-2-pyrimidinamine 
• 401816-63-5 3-{4-[2-(4-fluoro-phenyl)-6-triethoxymethyl-pyrazolo[1,5-a]pyridin-3-yl]-pyrimidin-2-ylamino}-propan-1-ol 
• 401816-64-6 2-(4-fluoro-phenyl)-3-[2-(3-hydroxy-propylamino)-pyrimidin-4-yl]-pyrazolo[1,5-a]pyridine-6-carboxylic acid ethyl ester 
• 401816-50-0 N-Cyclopropyl-4-[2-(4-fluorophenyl)-6-trifluoromethylpyrazolo[1,5-a]pyridin-3-yl]-2-pyrimidinamine 
• 401816-47-5 2-(4-fluorophenyl)-3-(3-(dimethylamino)-2-propenoyl)-6-trifluoromethylpyrazolo[1,5-a]pyridine 
• 401816-46-4 2-(4-fluorophenyl)-3-acetyl-6-trifluoromethylpyrazolo[1,5-a]pyridine 
• 372122-55-9 2-(4-fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine 
• 401816-45-3 3-(4-fluorophenyl)-2-(2-(5-trifluoromethyl)pyridyl)-2H-azirine 

Relevant academic research and scientific papers

SUBSTITUTED PYRAZOLO [1,5-α] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE

The present invention is directed to substituted pyrazolo[l,5-α]pyridines and related methods for their synthesis and use.

Pyrazolo[1,5-a]pyridines as p38 kinase inhibitors

(Chemical Equation Presented) A convergent synthesis of substituted pyrazolo[1,5-a]pyridines has been achieved either via a regioselective [3 + 2] cycloaddition of N-aminopyridines with alkynes or by thermal cyclization of disubstituted azirines. Subseque

PROCESS FOR THE PREPARATION OF CHEMICAL COMPOUNDS

The invention provides a process for preparing a compound of formula (I) and pharmaceutically acceptable derivatives thereof wherein: R0 and R1 are independently selected from H. halogen, C1-6alkyl, C1-6alkoxy.