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1-(2-Bromobenzyl)piperidine is an organic chemical compound that belongs to the class of piperidine derivatives. It is characterized by its white solid appearance and a molecular formula of C13H16BrN, with a molecular weight of 261.17 g/mol. This versatile intermediate is valued for its ability to undergo various chemical reactions, such as nucleophilic substitution and palladium-catalyzed coupling, which allows for the creation of a broad spectrum of derivatives with diverse chemical, physical, and biological properties. The presence of a bromine atom in its structure further enhances its utility as a starting material for additional functionalization through substitution or coupling reactions.

1459-22-9

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1459-22-9 Usage

Uses

Used in Organic Synthesis:
1-(2-Bromobenzyl)piperidine is used as a building block in organic synthesis for the creation of a variety of chemical compounds. Its reactivity and structural features make it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(2-Bromobenzyl)piperidine serves as a key intermediate for the synthesis of pharmaceuticals and bioactive compounds. Its ability to participate in multiple types of chemical reactions facilitates the development of new drugs with potential therapeutic applications.
Used in Chemical Reactions:
1-(2-Bromobenzyl)piperidine is utilized as a reactant in various chemical reactions, such as nucleophilic substitution and palladium-catalyzed coupling, to form a wide range of derivatives. These reactions are crucial for the modification of the compound's properties and its use in different applications.
Used in Further Functionalization:
The bromine atom in 1-(2-Bromobenzyl)piperidine makes it a useful starting material for further functionalization through substitution or coupling reactions. This allows chemists to tailor the compound's properties for specific applications, enhancing its versatility in chemical and pharmaceutical research.

Check Digit Verification of cas no

The CAS Registry Mumber 1459-22-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,5 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1459-22:
(6*1)+(5*4)+(4*5)+(3*9)+(2*2)+(1*2)=79
79 % 10 = 9
So 1459-22-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H16BrN/c13-12-7-3-2-6-11(12)10-14-8-4-1-5-9-14/h2-3,6-7H,1,4-5,8-10H2

1459-22-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2-bromophenyl)methyl]piperidine

1.2 Other means of identification

Product number -
Other names 1-(2-Bromobenzyl)piperidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1459-22-9 SDS

1459-22-9Relevant academic research and scientific papers

A Manganese Pre-Catalyst: Mild Reduction of Amides, Ketones, Aldehydes, and Esters

Kelly, Colin M.,McDonald, Robert,Sydora, Orson L.,Stradiotto, Mark,Turculet, Laura

, p. 15901 - 15904 (2017/12/13)

A new (N-phosphinoamidinate)manganese complex is shown to be a useful pre-catalyst for the hydrosilative reduction of carbonyl compounds, and in most cases at room temperature. The Mn-catalyzed reduction of tertiary amides to tertiary amines, with a useful scope, is demonstrated for the first time by use of this catalyst, and is competitive with the most effective transition-metal catalysts known for such transformations. Ketones, aldehydes, and esters were also successfully reduced under mild conditions by using this new Mn catalyst.

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