146140-99-0Relevant academic research and scientific papers
Additive-free radical cascade reaction of oxime esters: Synthesis of pyrroline-functionalized phenanthridines
Shao, Liming,Xue, Yijie,Xue, Dengqi,He, Qian,Ge, Qianwei,Li, Wei
, p. 12284 - 12293 (2020/11/10)
A variety of dihydropyrrole-functionalized phenanthridines were efficiently synthesized by the metal-free, radical cascade cyclization reaction of 2-isocyanobiphenyls with γ,δ- unsaturated oxime esters. The C-N/C-C/C-C bonds were formed via the oil bath method in a one-pot procedure with broad substrate applicability. The radical process was supported by kinetic isotope effect studies and radical inhibition studies.
GSK-3 INHIBITORS
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Page/Page column 85, (2018/06/12)
The disclosure generally relates to compounds of formula (I), including their salts, as well as compositions and methods of using the compounds to treat disorders associated with GSK-3.
Photocontrol over cooperative porphyrin self-assembly with phenylazopyridine ligands
Hirose, Takashi,Helmich, Floris,Meijer
supporting information, p. 304 - 309 (2013/02/23)
The cooperative self-assembly of chiral zinc porphyrins is regulated by a photoresponsive phenylazopyridine ligand (1; see picture). Porphyrin stacks depolymerize into dimers upon axial ligation and the strength of the coordination is regulated by its pho
Process for preparing a polyaromatic compound
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Page column 9-10, (2008/06/13)
The present invention concerns a process for preparing a polyaromatic compound comprising a concatenation of two aromatic cycles and carrying at least one amino group on one of the aromatic cycles. The process of the invention is characterized in that it consists of reacting an aromatic compound carrying at least one amino group and a leaving group with an arylboronic acid in an aqueous medium and in the presence of a palladium catalyst.
Preparation of 4-substituted 3-amino-2-chloropyridines, synthesis of a nevirapine analogue
Bakke,Riha
, p. 99 - 104 (2007/10/03)
A new method for preparing 3-amino-2-chloropyridines with a substituent (methyl, phenyl, carboxamide, methoxycarbonyl, acetyl, benzoyl and cyano) at the 4-position has been developed. An isoquinoline analogue of the reverse transcriptase inhibitor Nevirapine has been synthesized from the 4-amino-3-chloroisoquinoline.
Connection between metalation and cross-coupling strategies. A new convergent route to azacarbazoles
Rocca, Patrick,Marsais, Francis,Godard, Alain,Queguiner, Guy
, p. 49 - 64 (2007/10/02)
New convergent synthesis of azacarbazoles through metalation, cross-coupling reaction and intramolecular substitution via (2-aminobenzene)boronic acid and ortho-fluoroiodopyridines.
