1462379-43-6

Basic information

• Product Name: (E)-2-methoxyimino-2-(o-tolyl)acetic acid
• Synonyms: (E)-2-methoxyimino-2-(o-tolyl)acetic acid
• CAS NO: 1462379-43-6
• Molecular Weight: 193.202
• Mol File: 1462379-43-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-2-methoxyimino-2-(o-tolyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-methoxyimino-2-(o-tolyl)acetic acid(1462379-43-6)
• EPA Substance Registry System: (E)-2-methoxyimino-2-(o-tolyl)acetic acid(1462379-43-6)

Safety Data

• Hazardous Substances Data: 1462379-43-6(Hazardous Substances Data)

Upstream product

• 115199-21-8 methyl 2-methyl-α-methoxyiminophenylacetate 
• 144106-03-6 (Z)-2-(2-tolyl)-2-methoxyiminoacetic acid methyl ester 
• 593-56-6 N-methoxylamine hydrochloride 
• 298-12-4 Glyoxilic acid 
• 95-53-4 o-toluidine 
• 933-88-0 ortho-toluoyl chloride 
• 118-90-1 ortho-methylbenzoic acid 
• 34966-54-6 methyl 2-oxo-2-(o-tolyl)acetate 

Downstream Products

• 120974-97-2 methyl-(E)-2-(2-tolyl)-2-methoxyiminoacetate 
• 133409-72-0 methyl (E)-2-[2-(bromomethyl)phenyl]-2-(methoxyimino)acetate 
• 43121-43-3 trifloxystrobin 

Relevant articles and documents

(E)-2-(2-tolyl)-2-methoxyimino methyl acetate preparation method

The invention provides a (E)-2-(2-tolyl)-2-methoxyimino methyl acetate preparation method, which comprises: carrying out a saponification reaction on (Z)-2-(2-tolyl)-2-methoxyimino methyl acetate or (E/Z)-2-(2-tolyl)-2-methoxyimino methyl acetate or a mother liquor containing (E/Z)-2-(2-tolyl)-2-methoxyimino methyl acetate and an alkali to obtain (E)-2-(2-tolyl)-2-methoxyimino acetic acid, and carrying out a reaction on the obtained (E)-2-(2-tolyl)-2-methoxyimino acetic acid and a methylation reagent under an alkaline condition to obtain (E)-2-(2-tolyl)-2-methoxyimino methyl acetate. Accordingto the method disclosed by the invention, the Z configuration is converted into the E configuration product, so that the yield of the obtained E configuration product is obviously improved, the corrosion to equipment is small, the environmental pollution is not easily caused, and the method is an environment-friendly chemical synthesis process.

AN IMPROVED PROCESS FOR THE SYNTHESIS OF STROBILURIN FUNGICIDES VIZ TRIFLOXYSTROBIN AND KRESOXIM-METHYL

The present invention relates to an improved process for the synthesis of E-isomer of compound of formula (5). It further relates to the conversion of formula (5), wherein R is H, to Intermediate (I) and subsequently to substantially pure Trifloxystrobin, compound of formula (I) in good yield.