1462886-23-2Relevant academic research and scientific papers
An organocatalytic process for the hydrolytic cleavage of dithianes mediated by imidazolium ions: No harsh agents required
Myles, Lauren,Gathergood, Nicholas,Connon, Stephen J.
, p. 188 - 194 (2015)
A new, organocatalytic approach to the hydrolytic deprotection of dithianes has been developed involving a low-toxicity imidazolium-ion-based catalyst in an aqueous medium. A complimentary solvent-free method without added water and involving a sacrificial aldehyde is also reported. The catalyst does not appear to operate by a specific-acid catalysis mechanism.
A new generation of aprotic yet Bronsted acidic imidazolium salts: Low toxicity, high recyclability and greatly improved activity
Myles, Lauren,Gore, Rohitkumar G.,Gathergood, Nicholas,Connon, Stephen J.
, p. 2740 - 2746 (2013/10/08)
Catalysts which have low antimicrobial toxicity and are aprotic, yet which can act as Bronsted acidic catalysts in the presence of protic additives have been developed. The catalysts are recyclable, considerably more active (i.e. can be used at 10-50 times lower loadings) and of broader scope than their antecedent generation.
