146294-18-0Relevant articles and documents
Method for synthesizing quinoxaline compound under visible light induced iron catalysis condition
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Paragraph 0277-0281, (2021/07/10)
The invention belongs to the technical field of compound synthesis, and particularly relates to a method for synthesizing quinoxaline compounds under visible light induced iron catalysis conditions. The method comprises the following steps: by taking non-activated aliphatic amine and o-phenylenediamine as raw materials, under the action of a photosensitizer, under the illumination of visible light, reacting in a solvent at room temperature and under oxygen conditions to generate the quinoxaline compound. The method has better substrate universality and relatively mild reaction conditions, not only realizes synthesis of the quinoxaline compound for the first time, but also widens the field of organic synthesis.
ANDROGEN RECEPTOR ANTAGONISTS
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Paragraph 0366, (2019/08/26)
Compounds that inhibit the androgen receptor, pharmaceutical compositions comprising one or more of the compounds, as well as methods of treating cancer using such compounds are described.
Convenient Synthesis of 4-Methoxy-3-nitro-1,2-benzenediamine and its Conversion into 6-Methoxy-5-nitroquinoxalines
Grivas, Spiros,Tian, Wei
, p. 1109 - 1113 (2007/10/02)
4-Methoxy-3-nitro-1,2-benzenediamine (6) has been prepared through nitration of 5-methoxy-2,1,3-benzoselenadiazole, followed by reductive removal of the selenium.Cyclocondensation of 6 with α-dicarbonyl compounds afforded the title quinoxalines, some of them novel and not easily obtainable by direct nitration.Methyl- or phenylglyoxal gave mixtures of quinoxalines in proportions strongly influenced by the acidity of the reaction medium.