146335-26-4

Basic information

• Product Name: methyl 2-benzyloxy-5-iodobenzoate
• Synonyms: methyl 2-benzyloxy-5-iodobenzoate
• CAS NO: 146335-26-4
• Molecular Weight: 368.171
• Mol File: 146335-26-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2-benzyloxy-5-iodobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-benzyloxy-5-iodobenzoate(146335-26-4)
• EPA Substance Registry System: methyl 2-benzyloxy-5-iodobenzoate(146335-26-4)

Safety Data

• Hazardous Substances Data: 146335-26-4(Hazardous Substances Data)

Usage

General Description

Methyl 2-benzyloxy-5-iodobenzoate is a chemical compound with the molecular formula C15H13IO3. It is a member of the benzoate ester family, containing a methyl ester group, a benzyloxy group, and an iodine atom attached to a benzene ring. methyl 2-benzyloxy-5-iodobenzoate is typically used in organic synthesis as a building block for the creation of pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure and reactivity make it useful in the formation of carbon-carbon and carbon-oxygen bonds, which are essential in the construction of complex organic molecules. Methyl 2-benzyloxy-5-iodobenzoate is an important intermediate in the production of various chemical compounds and plays a significant role in the field of chemical research and development.

Upstream product

• 186581-53-3 diazomethane 
• 146335-32-2 2-benzyloxy-5-iodobenzoic acid 
• 4068-75-1 methyl 5-iodosalicylate 
• 100-39-0 benzyl bromide 
• 134038-89-4 2-benzyloxy-5-iodobenzaldehyde 

Downstream Products

• 143164-87-8 (2S,3R)-2-((2S,4R)-5-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-4-hydroxy-pentanoylamino)-3-{4,4'-bis-benzyloxy-3'-[(S)-2-benzyloxycarbonylamino-2-(2-trimethylsilanyl-ethoxycarbonyl)-ethyl]-biphenyl-3-yl}-3-hydroxy-propionic acid methyl ester 
• 143164-87-8 (2R,3S)-2-((2S,4R)-5-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-4-hydroxy-pentanoylamino)-3-{4,4'-bis-benzyloxy-3'-[(S)-2-benzyloxycarbonylamino-2-(2-trimethylsilanyl-ethoxycarbonyl)-ethyl]-biphenyl-3-yl}-3-hydroxy-propionic acid methyl ester 
• 146335-31-1 4,4'-dibenzyloxy-3-<(S)-2-(tert-butoxycarbonylamino)-2-methoxycarbonyl-(R)-1-hydroxyethyl>-3'-(1,3-dioxan-2-yl)biphenyl 
• 146335-31-1 4,4'-dibenzyloxy-3-<(R)-2-(tert-butoxycarbonylamino)-2-methoxycarbonyl-(R)-1-hydroxyethyl>-3'-(1,3-dioxan-2-yl)biphenyl 
• 146335-31-1 3-(4,4'-Bis-benzyloxy-3'-[1,3]dioxan-2-yl-biphenyl-3-yl)-2-tert-butoxycarbonylamino-3-hydroxy-propionic acid methyl ester 
• 143164-86-7 C₆₇H₈₀N₄O₁₅Si 
• 871206-25-6 (2S,3R)-2-((2S,4R)-2-Amino-5-benzyloxycarbonylamino-4-hydroxy-pentanoylamino)-3-[4,4'-bis-benzyloxy-3'-((S)-2-benzyloxycarbonylamino-2-pentafluorophenyloxycarbonyl-ethyl)-biphenyl-3-yl]-3-hydroxy-propionic acid methyl ester 
• 146388-30-9 (7R,8S,11S,14S)-5,17-Bis-benzyloxy-14-benzyloxycarbonylamino-11-((R)-3-benzyloxycarbonylamino-2-hydroxy-propyl)-7-hydroxy-10,13-dioxo-9,12-diaza-tricyclo[14.3.1.1^2,6]henicosa-1⁽¹⁹⁾,2⁽²¹⁾,3,5,16⁽²⁰⁾,17-hexaene-8-carboxylic acid methyl ester 
• 146388-31-0 (7R,8S,11S,14S)-5,17-Bis-benzyloxy-14-benzyloxycarbonylamino-11-((R)-3-benzyloxycarbonylamino-2-hydroxy-propyl)-7-hydroxy-10,13-dioxo-9,12-diaza-tricyclo[14.3.1.1^2,6]henicosa-1⁽¹⁹⁾,2⁽²¹⁾,3,5,16⁽²⁰⁾,17-hexaene-8-carboxylic acid 
• 146335-30-0 4,4'-dibenzyloxy-3-<(R,S)-2-(tert-butoxycarbonylamino)-2-methoxycarbonyl-1-oxoethyl>-3'-(1,3-dioxan-2-yl)biphenyl 
• 146335-28-6 4,4'-dibenzyloxy-3-(1,3-dioxan-2-yl)-3'-carboxybiphenyl 
• 146335-29-7 4,4'-Bis-benzyloxy-3'-[1,3]dioxan-2-yl-biphenyl-3-carbonyl chloride 
• 146388-29-6 (2S,3R)-2-((2S,4R)-5-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-4-hydroxy-pentanoylamino)-3-[4,4'-bis-benzyloxy-3'-((S)-2-benzyloxycarbonylamino-2-pentafluorophenyloxycarbonyl-ethyl)-biphenyl-3-yl]-3-hydroxy-propionic acid methyl ester 
• 143164-84-5 3-<(S)-2-(benzyloxycarbonylamino)-2-(trimethylsilylethoxycarbonyl)ethyl>-3'-<(S)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)-(R)-1-hydroxyethyl>-4,4'-dibenzyloxybiphenyl 

Relevant articles and documents

Aminoalcohol derivatives

The present invention relates to a compound formula [I]: wherein R1 is hydrogen or halogen, R2 is hydrogen or an amino protective group, R3 is hydrogen or lower alkyl, X is bond, —CH2— or —O—, and Y is ?in which R4 is lower alkoxycarbonyl, ?in which R5 is carboxy(lower)alkyl, etc., ?in which R6 is hydroxy, etc., and so on, or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.

Total synthesis of the biphenomycins; V. Synthesis of biphenomycin A

The total synthesis of biphenomycin A is described. Two of the five stereogenic centres were formed by enantioselective hydrogenation of the corresponding didehydroamino acids using the rhodium-DIPAMP catalyst and the two stereogenic centres of the α-amin