146348-14-3

Upstream product

• 67-56-1 methanol 
• 173340-19-7 (3S)-1-((S)-1-phenylethyl)-5-oxo-3-pyrrolidinecarboxylic acid 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 97-65-4 2-methylenesuccinic acid 

Downstream Products

• 188641-35-2 (4S,1'S)-4-hydroxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 641634-56-2 (S)-4-((benzyloxy)methyl)-1-((S)-1-phenylethyl)pyrrolidin-2-one 
• 191348-04-6 (S)-3-formylpyrrolidine-1-carboxylic acid t-butyl ester 
• 199174-24-8 tert-butyl (3S)-3-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 173724-95-3 (S)-1-((S)-1-phenylethyl)-3-hydroxymethylpyrrolidine 

Relevant academic research and scientific papers

SPIRO CONDENSED PIPERIDNES AS MODULATORS OF MUSCARINIC RECEPTORS

The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

BENZOIC ACID COMPOUNDS AND USE THEREOF AS MEDICAMENTS

Benzoic acid compounds of the formula STR1 wherein each symbol is as defined in the specification, optical isomers thereof and pharmaceutically acceptable salts thereof; pharmaceutical composition comprising this compound and pharmaceutically acceptable additive; and serotonin 4 receptor agonists, gastrointestinal prokinetic agents and therapeutic agents for various gastrointestinal diseases, which comprise this compound as active ingredient. The compounds of the present invention have high and selective affinity for serotonin 4 receptor, and show agonistic effects thereon. Accordingly, they are useful medications for the prophylaxis and treatment of various gastrointestinal diseases, central nervous disorders, cardiac function disorders, urinary diseases, and the like, as well as useful anti-nociceptors for analgesic use which increase threshold of pain.