1464-12-6

Upstream product

• 1464-11-5 4-benzyloxyindole-3-acetonitrile 
• 2380-94-1 1H-indol-4-ol 
• 20289-26-3 4-benzyloxy-1H-indole 
• 13523-95-0 4-benzyloxy-3-dimethylaminomethylindole 
• 100-39-0 benzyl bromide 
• 33797-51-2 eschenmoser's salt 
• 74-88-4 methyl iodide 

Downstream Products

• 144923-56-8 4-Nitrophenyl <(4-Benzyloxy)-1H-indol-3-yl>acetate 
• 200066-59-7 (5-{(S)-2-[2-(4-Benzyloxy-1H-indol-3-yl)-acetylamino]-3-carbamoyl-propionylamino}-pentyl)-carbamic acid tert-butyl ester 
• 144923-49-9 N-(5-{3-[3-(3-Amino-propylamino)-propylamino]-propylamino}-pentyl)-2-(4-benzyloxy-1H-indol-3-yl)-acetamide 
• 152916-20-6 25-<4-benzyloxy-1H-indol-3-yl>-2,2-dimethyl-4,24-dioxo-3-oxa-5,9,13,17,23-pentaazapentacosane-9,13-dicarboxylic acid bis(1,1-dimethylethyl) ester 
• 145118-26-9 N-Acetyl-N'-acetyl>-L-alanyl>hexane-1,6-diamine 
• 145118-34-9 N-acetyl>-L-alanyl>-N'-2,N⁶-bis<(benzyloxy)carbonyl>-L-lysyl>hexane-1,6-diamine 
• 1748-41-0 2-(4-(benzyloxy)-1H-indol-3-yl)-N-methylethan-1-amine 
• 1467-95-4 ethyl-[2-(4-benzyloxy-indol-3-yl)-ethyl]-amine 

Relevant academic research and scientific papers

General synthesis of β-alanine-containing spider polyamine toxins and discovery of Nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors

Certain spiders contain large pools of polyamine toxins, which are putative pharmacological tools awaiting further discovery. Here we present a general synthesis strategy for this class of toxins and prepare five structurally varied polyamine toxins. Elec

Facile synthesis of 6-hydroxyindole-3-acetic acid: On the structure of the aromatic subunit of nephilatoxin-1~6

A facile synthesis of 6-hydroxyindole-3-acetic acid 1a, which is the proposed aromatic subunit of NPTX-1~6, is described. Radical cyclization of isonitrile 2 successfully afforded 9 in high yield. The aromatic subunit of NPTX-1~6 was confirmed as 4-hydroxyindole-3-acetic acid 12 by comparison of the 1H-NMR spectra with those of authentic 4- and 6-hydroxyindole-3-acetic acids.

Characterization and synthesis of a new calcium antagonist from the venom of a fishing spider

A new calcium antagonist, CNS 2103, is isolated from the venom of a fishing spider, Dolomedes okefinokensis. The structure of this compound is derived from spectroscopic data, including tandem mass spectrometry. A flexible, convergent synthesis of CNS 2103 is described.