13523-95-0

Usage

Chemical Properties

White Solid

Uses

A A benzyloxyindole derivative, also an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine

Upstream product

• 50-00-0 formaldehyd 
• 20289-26-3 4-benzyloxy-1H-indole 
• 124-40-3 dimethyl amine 
• 20876-37-3 2-benzyloxy-6-nitrotoluene 
• 100-44-7 benzyl chloride 
• 39731-09-4 4-benzyloxylindole-2-carboxylic acid 
• 2380-94-1 1H-indol-4-ol 
• 100-39-0 benzyl bromide 

Downstream Products

• 1464-12-6 2-(4-(benzyloxy)-1H-indol-3-yl)acetic acid 
• 109249-04-9 2-(4-(benzyloxy)-1H-indol-3-yl)ethanamine 
• 1464-11-5 4-benzyloxyindole-3-acetonitrile 
• 2873-49-6 1-<4-(benzyloxy)indol-3-yl>-2-nitropropane 
• 152916-20-6 25-<4-benzyloxy-1H-indol-3-yl>-2,2-dimethyl-4,24-dioxo-3-oxa-5,9,13,17,23-pentaazapentacosane-9,13-dicarboxylic acid bis(1,1-dimethylethyl) ester 
• 144923-49-9 N-(5-{3-[3-(3-Amino-propylamino)-propylamino]-propylamino}-pentyl)-2-(4-benzyloxy-1H-indol-3-yl)-acetamide 
• 144923-56-8 4-Nitrophenyl <(4-Benzyloxy)-1H-indol-3-yl>acetate 

Relevant academic research and scientific papers

SAR of psilocybin analogs: Discovery of a selective 5-HT2C agonist

An SAR study of psilocybin and psilocin derivatives reveals that 1-methylpsilocin is a selective agonist at the h5-HT2C receptor. The corresponding phosphate derivative, 1-methylpsilocybin, shows efficacy in an animal model for obsessive-compul

Facile synthesis of 6-hydroxyindole-3-acetic acid: On the structure of the aromatic subunit of nephilatoxin-1~6

A facile synthesis of 6-hydroxyindole-3-acetic acid 1a, which is the proposed aromatic subunit of NPTX-1~6, is described. Radical cyclization of isonitrile 2 successfully afforded 9 in high yield. The aromatic subunit of NPTX-1~6 was confirmed as 4-hydroxyindole-3-acetic acid 12 by comparison of the 1H-NMR spectra with those of authentic 4- and 6-hydroxyindole-3-acetic acids.

Characterization and synthesis of a new calcium antagonist from the venom of a fishing spider

A new calcium antagonist, CNS 2103, is isolated from the venom of a fishing spider, Dolomedes okefinokensis. The structure of this compound is derived from spectroscopic data, including tandem mass spectrometry. A flexible, convergent synthesis of CNS 2103 is described.