146950-68-7

Basic information

• Product Name: 3,4-Pyridinediamine,N4-cyclopropyl-(9CI)
• Synonyms: 3,4-Pyridinediamine,N4-cyclopropyl-(9CI);3-Amino-4-(cyclopropylamino)pyridine;N4-Cyclopropyl-3,4-pyridinediaMine;4-N-cyclopropylpyridine-3,4-diaMine;3,4-PyridinediaMine, N4-cyclopropyl-;N4-Cyclopropylpyridine-3,4-diaMine
• CAS NO: 146950-68-7
• Molecular Formula: C₈H₁₁N₃
• Molecular Weight: 149.19304
• Product Categories: PYRIDINE;Heterocycle-Pyridine series
• Mol File: 146950-68-7.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 353.5ºC at 760 mmHg
• Flash Point: 167.6ºC
• Appearance: /
• Density: 1.312g/cm3
• Vapor Pressure: 3.56E-05mmHg at 25°C
• Refractive Index: 1.73
• Storage Temp.: 2-8°C(protect from light)
• PKA: 10.52±0.36(Predicted)
• CAS DataBase Reference: 3,4-Pyridinediamine,N4-cyclopropyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Pyridinediamine,N4-cyclopropyl-(9CI)(146950-68-7)
• EPA Substance Registry System: 3,4-Pyridinediamine,N4-cyclopropyl-(9CI)(146950-68-7)

Safety Data

• Hazardous Substances Data: 146950-68-7(Hazardous Substances Data)

Usage

General Description

3,4-Pyridinediamine,N4-cyclopropyl-(9CI) is a chemical compound with the molecular formula C7H10N4. It is also known as 3,4-Diaminopyridine and is a derivative of pyridine. 3,4-Pyridinediamine,N4-cyclopropyl-(9CI) is commonly used as a building block in organic synthesis and pharmaceutical research. It has been studied for its potential use in the treatment of various medical conditions, including neurological disorders and autoimmune diseases. Additionally, it has been investigated for its potential role as a corrosion inhibitor in industrial applications. However, further research is needed to fully understand the potential uses and effects of 3,4-Pyridinediamine,N4-cyclopropyl-(9CI) in various fields.

InChI:InChI=1/C8H11N3/c9-7-5-10-4-3-8(7)11-6-1-2-6/h3-6H,1-2,9H2,(H,10,11)

Upstream product

• 380605-28-7 N-cyclopropyl-3-nitropyridin-4-amine 
• 1796-84-5 4-ethoxy-3-nitropyridine 
• 5435-54-1 4-hydroxy-3-nitropyridine 
• 626-64-2 pyridin-4-ol 
• 13091-23-1 4-chloro-3-nitropyridine 
• 31872-62-5 4-methoxy-3-nitro-pyridine 

Downstream Products

• 1383451-33-9 4-(5-bromo-2-((1-cyclopropyl-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)methyl)-1H-indol-1-yl)butyl 4-methylbenzensulfonate 

Relevant articles and documents

1-PYRAZOLYL, 5-, 6- DISUBSTITUTED INDAZOLE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

The present invention is directed to substituted certain 1-pyrazolyl, 5-, 6- disubstituted indazole derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, and ring A are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of diseases, such as Parkinson's disease, in which LRRK-2 kinase is involved.

QUINAZOLINE BASED RESPIRATORY SYNCYTIAL VIRUS INHIBITORS

Compounds of Formula (I), wherein R1, R2, R3, R4 and n are defined herein, are useful as inhibitors of RSV.

Non-benzimidazole containing inhibitors of respiratory syncytial virus

Several non-benzimidazole containing inhibitors of respiratory syncytial virus are described. Core template modification, analysis of antiviral activity, physicochemistry and optimisation of properties led to the thiazole-imidazole 13, that showed a good potency and pharmacokinetic profile in the rat.