1470-36-6Relevant academic research and scientific papers
INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS
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Page/Page column 63; 74, (2013/05/23)
The invention relates to indanone/indandione derivatives and heterocyclic analogs of Formula (I) wherein Ar1, A, B, L1, Y, Z, and (R1)n n are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments, especially as NPS receptor antagonists.
Sarcosine based indandione hGlyT1 inhibitors
Thomson, Christopher G.,Duncan, Karen,Fletcher, Stephen R.,Huscroft, Ian T.,Pillai, Gopalan,Raubo, Piotr,Smith, Alison J.,Stead, Darren
, p. 1388 - 1391 (2007/10/03)
A series of sarcosine based indandione hGlyT1 inhibitors has been developed. Optimization of substitution around the indandione and sarcosine moieties has led to highly potent inhibitors at hGlyT1, which show selectivity over a number of other receptors.
