147022-22-8

Basic information

• Product Name: 4-chlorophenyl-1-naphthylmethanol
• Synonyms: 4-chlorophenyl-1-naphthylmethanol
• CAS NO: 147022-22-8
• Molecular Weight: 268.743
• Mol File: 147022-22-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-chlorophenyl-1-naphthylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chlorophenyl-1-naphthylmethanol(147022-22-8)
• EPA Substance Registry System: 4-chlorophenyl-1-naphthylmethanol(147022-22-8)

Safety Data

• Hazardous Substances Data: 147022-22-8(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 90-13-1 1-Chloronaphthalene 
• 7519-91-7 tris(4-chlorophenyl)boroxine 
• 66-77-3 1-naphthaldehyde 
• 1679-18-1 4-Chlorophenylboronic acid 
• 1591-44-2 (4-chlorophenyl)(naphthalen-1-yl)methanone 

Downstream Products

• 1591-43-1 1-(4-chlorobenzyl)naphthalene 
• 147022-04-6 1-[(4-Chloro-phenyl)-naphthalen-1-yl-methyl]-1H-imidazole 

Relevant articles and documents

C60-catalyzed preparation of aryl and heteroaryl magnesium and zinc reagents using Mg/LiCl

Addition of a catalytic amount of C60 fullerene (3 mol %) catalyzes the insertion of magnesium to polycyclic aromatic halides, allowing the preparation of the corresponding Grignard reagents in good yields. Furthermore, the use of a cocktail of metallic salts (Mg, ZnCl2, LiCl) in the presence of C60 fullerene (3 mol %) allows preparation of some functionalized polyaromatic zinc reagents. The resulting organomagnesium and organozinc reagents efficiently underwent reactions with electrophiles, such as an aldehyde, an acid chloride, an allylic bromide, or an aryl iodide.

Use of cheaper metal than Rh, CHCl3-free Pd catalyst, in 1,2-addition of aromatic aldehydes with arylboronic acids

Pd(OAc)2-(±)-tol-BINAP-catalyzed arylation reaction of aromatic aldehydes with arylboronic acids in the absence of CHCl3 is described.