147088-89-9

Basic information

• Product Name: Methanone, 1H-pyrrole-2,4-diylbis[phenyl-
• CAS NO: 147088-89-9
• Molecular Formula: C18H13NO2
• Molecular Weight: 275.307
• Mol File: 147088-89-9.mol

Chemical Properties

• CAS DataBase Reference: Methanone, 1H-pyrrole-2,4-diylbis[phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, 1H-pyrrole-2,4-diylbis[phenyl-(147088-89-9)
• EPA Substance Registry System: Methanone, 1H-pyrrole-2,4-diylbis[phenyl-(147088-89-9)

Safety Data

• Hazardous Substances Data: 147088-89-9(Hazardous Substances Data)

Upstream product

• 109-97-7 pyrrole 
• 98-88-4 benzoyl chloride 
• 147089-32-5 4-(2-phenyl-1,3-benzodithiol-2-yl)-2-(2-phenyl-1,3-benzoxathiol-2-yl)pyrrole 
• 147089-16-5 3-(2-phenyl-1,3-benzodithiol-2-yl)-1-phenylsulfonylpyrrole 
• 147089-24-5 3-(2-phenyl-1,3-benzodithiol-2-yl)pyrrole 
• 81453-99-8 1-(phenylsulfonyl)-3-benzoylpyrrole 
• 7126-41-2 3-benzoylpyrrole 
• 7697-46-3 phenyl(1H-pyrrol-2-yl)methanone 
• 147089-53-0 2,4-bis(2-phenyl-1,3-benzodithiol-2-yl)pyrrole 
• 147089-06-3 4-benzoyl-2-(2-phenyl-1,3-benzodithiol-2-yl)pyrrole 
• 147089-42-7 2-benzoyl-4-(2-phenyl-1,3-benzodithiol-2-yl)pyrrole 

Downstream Products

• 173322-56-0 5,10-diphenyl-8-aza-16-carba-5,10,15,17-tetrahydrotripyrrane 
• 499214-39-0 (2,4-dibenzoylpyrrol-1-yl)acetic acid ethyl ester 
• 173322-52-6 2,4-bis(1-phenyl-1-hydroxymethyl)pyrrole 

Relevant articles and documents

Doubly N-confused calix[4]pyrrole prepared by rational synthesis

Doubly N-confused calix[4]pyrrole 4 is prepared in high yield by the [3 + 1] condensation of tripyrrane 3 with 2,4-dihdoxymethylpyrrole 2 under acid-catalysed conditions.

Substituted pyrrol-1-ylacetic acids that combine aldose reductase enzyme inhibitory activity and ability to prevent the nonenzymatic irreversible modification of proteins from monosaccharides

Starting from the known inhibitory activity of (3-benzoylpyrrol-1-yl)acetic acid (I) and (2-benzoylpyrrol-1-yl)acetic acid (II), a series of 3-aroyl and 2,4-bis-aroyl derivatives (54-75) were synthesized and tested for inhibition of aldose reductase, an e

Stepwise syntheses of core-modified, meso-substituted porphyrins

Simple conditions are discovered to afford modified tripyrrin derivatives by condensation of 2,5-bis(α-hydroxymethyl)pyrrole, thiophene and furan derivatives with pyrrole in the presence of acid catalyst. The core-modified porphyrins were synthesized by acid catalyzed 3+1 condensation of modified tripyrrins with 2,5-bis(α-hydroxymethyl)-substituted pyrrole, thiophene or furan. This new process gives a single porphyrin isomer and overcomes the synthetic problems associated with separation and purification of regioisomeric mixtures.

General Methods for Synthesizing 2,4-Diacylpyrroles and their Precursors Containing One or Two Masked Acyl Groups

A thorough study of the synthesis of 2,4-diacylpyrroles by direct acylation of pyrrole and 2- and 3-acylpyrroles is reported.Among these, Friedel-Crafts acylation of 3-acylpyrroles is the most general and advantageous method because it utilises easily accessible starting materials.In addition it is always regiospecific and readily provides 2,4-diacylpyrroles containing identical or different acyl groups in very high yields (81-100percent) under mild conditions, Alternative procedures concern the synthesis of precursors of 2,4-diacylpyrroles containing one or two acyl groups masked by a 1,3-benzodithiolyl or 1,3-benzoxathiolyl group and subsequent hydrolysis with HgO-35percent aq.HBF4-Me2SO.Overall yields are always good (52-60percent).Indirect acylation constitutes a secure complement to direct acylation when it is necessary to operate in the presence of protected acyl groups.