147197-80-6Relevant articles and documents
Supported palladium-catalyzed carbonylative cyclization of 2-bromonitrobenzenes and alkynes to access quinolin-4(1H)-ones
Li, Chenyu,Li, Chuan-Ying,Lu, Wangyang,Wang, Jian-Shu,Wu, Xiao-Feng,Xu, Tiefeng,Ying, Jun
, p. 81 - 87 (2022/03/15)
A palladium supported on graphitic carbon nitride (Pd/g-C3N4) catalyzed carbonylative cyclization of 2-bromonitrobenzenes and alkynes has been developed for the expedite construction of quinolin-4(1H)-one scaffolds. By using a low loading heterogeneous palladium catalyst, Mo(CO)6 as both the CO surrogate and the reductant, and nitroarenes as the nitrogen source, the reaction proceeded well to give a variety of quinolin-4(1H)-ones in good to excellent yields.
Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: Identification as antimitotic agents interacting with tubulin
Kuo,Lee,Juang,Lin,Wu,Chang,Lednicer,Paull,Lin,Hamel,Lee
, p. 1146 - 1156 (2007/10/02)
A series of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds have been synthesized and evaluated as cytotoxic compounds and as antimitotic agents interacting with tubulin. The 2-phenyl-4-quinolones (22-30) with substituents
