147256-04-0

Basic information

• Product Name: Ethanone, 1-[4-(1-hydroxy-1-phenylethyl)phenyl]-
• CAS NO: 147256-04-0
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• Mol File: 147256-04-0.mol

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-(1-hydroxy-1-phenylethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(1-hydroxy-1-phenylethyl)phenyl]-(147256-04-0)
• EPA Substance Registry System: Ethanone, 1-[4-(1-hydroxy-1-phenylethyl)phenyl]-(147256-04-0)

Safety Data

• Hazardous Substances Data: 147256-04-0(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 100-52-7 benzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 583-05-1 1-phenylpentane-1,4-dione 

Relevant articles and documents

Reductive Coupling of Aromatic Aldehydes and Ketones under Electrochemical Conditions

Reductive coupling of o-substituted carbonyl compounds and m-substituted carbonyl compounds by the direct transfer of electron to carbonyl group respectively gave 1-(4-(1-hydroxy-1-phenylethyl/methyl)phenyl)ethanones/methanones and 2,3-bis(3-substitutedph

Phenyl-Carbonyl Coupling Reactions Promoted by Samarium Diiodide and Hexamethylphosphoramide

By mediation of samarium diiodide and hexamethylphosphoramide, benzaldehydes and acetophenones underwent self- and cross-couplings to give the products having linkages at the para-carbons of phenyl rings and the carbonyl groups. The phenyl-carbonyl coupling of 2,5-dimethoxybenzaldehyde generated a Sm(III)-enolate intermediate, which was trapped by alkyl halides in a stereospecific manner to give uncommon 1,4-dialkyl-2,5-cyclohexadiene-1-carboxaldehydes. The benzaldehydes bearing tethered carbonyl chains proceeded with intramolecular phenyl-carbonyl couplings to afford fused benzocycles.

Samarium diiodide / hexamethylphosphoramide promoted dimerization of benzaldehydes

Benzaldehyde, its ortho- and meta-substituted derivatives and acetophenone underwent dimerization reactions on treatment with samarium(II) iodide in the presence of HMPA. Intramolecular phenyl-carbonyl coupling reactions were similarly carried out.