1473360-07-4

Upstream product

• 98-88-4 benzoyl chloride 
• 121424-20-2 1,2,3,4-tetra-O-acetyl-6-(4-methylbenzenesulfonate)-α-D-mannopyranose 
• 1473360-05-2 p-tolyl 6-azido-2,3,4-tri-O-acetyl-6-deoxy-1-thio-α-D-mannopyranoside 
• 106-45-6 para-thiocresol 
• 210170-40-4 1,2,3,4-tetra-O-acetyl-6-azido-6-deoxy-α-D-mannopyranoside 

Downstream Products

• 863915-11-1 6-azido-2,3,4-tri-O-benzoyl-6-deoxy-α-D-mannopyranose-1-O-trichloroacetimidate 
• 1473360-01-8 3-O-(6'-azido-2',3',4'-tri-O-benzoyl-6'-deoxy-α-D-mannopyranosyl)-1,2-isopropylidene-sn-glycerol 

Relevant academic research and scientific papers

Synthesis and antiviral evaluation of 6'-acylamido-6'-deoxy-α-d- mannoglycerolipids

Eight new aminomannoglycerolipids (2a-h) with linear, branched, or aromatic acyl chains were synthesized and evaluated for their anti-influenza A virus (IAV) activity. By comparing six mannosyl donors with different protecting and leaving groups, the critical glycosylation reaction employed mannosyl trichloroacetimidate with 2-O-benzoyl protecting group as the donor to give the glycoside with absolute α-anomeric selectivity. The bioactivity results showed that the branched compound 2g could effectively inhibit IAV multiplication in MDCK cells with IC50 69.9 μM.