147389-32-0

Upstream product

• 118-93-4 o-hydroxyacetophenone 
• 56-40-6 glycine 

Downstream Products

• 143675-24-5 {o-hydroxyacetophenone glycine^(2-)}SnBu₂ 
• 554-68-7 triethylamine hydrochloride 
• 914461-19-1 [Cu(o-hydroxyacetophenoneglycine^(2-))(thiophene-o-carboxaldene-p-toluidine)(H₂O)] 
• 914461-13-5 [Cu(o-hydroxyacetophenoneglycine^(2-))(bis(benzylidene)ethylenediamine)(H₂O)] 
• 914461-18-0 [Ni(o-hydroxyacetophenoneglycine^(2-))(thiophene-o-carboxaldene-p-toluidine)(H₂O)] 
• 914461-12-4 [Ni(o-hydroxyacetophenoneglycine^(2-))(bis(benzylidene)ethylenediamine)(H₂O)] 
• 914461-15-7 [Cd(o-hydroxyacetophenoneglycine^(2-))(bis(benzylidene)ethylenediamine)(H₂O)] 
• 914461-21-5 [Cd(o-hydroxyacetophenoneglycine^(2-))(thiophene-o-carboxaldene-p-toluidine)(H₂O)] 
• 914461-20-4 [Zn(o-hydroxyacetophenoneglycine^(2-))(thiophene-o-carboxaldene-p-toluidine)(H₂O)] 
• 914461-16-8 [Mn(o-hydroxyacetophenoneglycine^(2-))(thiophene-o-carboxaldene-p-toluidine)(H₂O)] 
• 914461-11-3 [Co(o-hydroxyacetophenoneglycine^(2-))(bis(benzylidene)ethylenediamine)(H₂O)] 
• 914461-17-9 [Co(o-hydroxyacetophenoneglycine^(2-))(thiophene-o-carboxaldene-p-toluidine)(H₂O)] 
• 143675-23-4 {o-hydroxyacetophenone glycine^(2-)}SnMe₂ 

Relevant academic research and scientific papers

Synthesis, characterization and biological evaluation of a novel vanadium complex as a possible anticancer agent

Chemotherapeutics are the sole treatment modality for cancer patients at advanced condition. In the pursuit of getting an efficient, selective and non toxic anticancer agent that has not been discovered yet, we rationally synthesized a vanadium complex with a Schiff base ligand N-(-2-hydroxyacetophenone) glycinate. Characterization of the synthesized complex VO(NG)2, was carried out with the help of various spectroscopic means. The complex proved to be a broad spectrum anticancer agent with significantly less toxicity towards normal cells as evident from cell viability assay. Furthermore, VO(NG)2 treatment increased the life-span of ascitic and solid tumor bearing Swiss albino mice and did not show any significant symptomatic sub acute toxicity on normal Swiss albino mice.

Synthesis, characterization and biological properties of a novel copper complex

The study of copper complex in relation to cancer is important in many ways. A novel copper complex has been synthesized with non toxic ligand, viz. potassium salt of N-(2-hydroxy acetophenone) glycinate (NHAG). The structure of the complex has been determined by spectroscopic means. Toxicity and antitumor property of the complex has been studied in vivo. Though the complex is toxic at higher doses, lower non toxic doses of the complex deplete glutathione (GSH). GSH depleting property of the complex may be utilized to sensitize drug resistant cells where resistance is due to elevated level of GSH.

Characterization and antifungal study of genuine oxovanadium(IV) mixed-ligand complexes with schiff bases

New oxovanadium(IV) complexes [VO(L)(A)] (KHL = potassium salt of o-hydroxy-acetophenoneglycine, A1 = 2,2′-bipyridylamine, A 2 = bis(benzylidene)ethylenediamine, A3 = thiophene-o-carboxaldeneaniline, A4 = thioph