14747-96-7

Upstream product

• 5382-00-3 Diphenyl phosphorochloridite 
• 54305-75-8 N,N-diethylaminodiiodophosphine 
• 139-02-6 sodium phenoxide 
• 109-89-7 diethylamine 
• 2283-11-6 hexaethylphosphoric triamide 
• 108-95-2 phenol 
• 1069-08-5 diethylphosphoramidous dichloride 
• 14684-28-7 phenyl phosphorous tetraethyldiamide 
• 74378-21-5 C-phenylcalix[4]resorcinarene 
• 132958-38-4 tetrahexylcalix[4]resorcinarene 

Downstream Products

• 65747-91-3 ((E)-2-Diethylamino-propenyl)-phosphonic acid diphenyl ester 
• 3577-87-5 diphenyl methyl phosphite 
• 113125-24-9 dimeric dihydroxyacetone phosphate ethyl hemiacetal barium salt 
• 7330-17-8 isopropyl diphenyl phosphite 
• 7526-26-3 diphenyl methylphosphonate 
• 1709-50-8 N,N-diethylbenzenesulfonamide 
• 135052-85-6 ((3aR,5S,5aR,8aS,8bR)-2,2,7,7-Tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-ylmethyl)-phosphonic acid diphenyl ester 
• 135052-86-7 [(3aR,4S,6S,7R,7aS)-6-Methoxy-7-(4-methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethyl]-phosphonic acid diphenyl ester 
• 105751-11-9 H-Glu-Ser(PO₃Ph₂)-Leu-OH*CF₃CO₂H 
• 105751-09-5 Boc-Glu(OBzl)-Ser(PO₃Ph₂)-Leu-OBzl 
• 106111-03-9 Boc-Ser(PO₃Ph₂)-Leu-OBzl 
• 106128-52-3 Boc-Ser(PO₃Ph₂)-ONb 
• 105751-07-3 N^α-(t-butoxycarbonyl)-O-(diphenylphosphono)-L-serine 
• 7434-44-8 phosphoric acid butyl ester-diphenyl ester 

Relevant academic research and scientific papers

Dismutation of arylene phosphorodiamidites: Specific features and aspects of preparative use

The dismutation of arylene phosphorodiamidites derived from the simplest phenols and naphthols and of their dibasic analogs was studied. The main regular trends of this process and the limits of its synthetic applicability were determined. Pleiades Publishing, Inc., 2006.

Dismutation of diamidoarylphosphites

Some examples of spontaneous dismutation of diamidoarylphosphites in different solvents were studied, and features of the process were revealed.

Cyclophosphorylation of polyphenols by diamidoarylphosphites

It was found that the cyclophosphorylation of polyphenols by diamidoarylphosphites proceeds via the rupture of only one P-N bond and one P-O bond, the second P-N bond remaining intact. It is supposed that the unusual lack of reactivity of the P-N bond is due to the spatial arrangement of the amido group with respect to the reaction site in phosphorylated intermediates 5.

Synthesis of Casein-Related Peptides and Phosphopeptides. VII. The efficient Synthesis of Ser(P)-Containing peptides by the Use of Boc-Ser(PO3R2)-OH Derivatives

A new approach to the synthesis of Ser(PO3R2)-containing peptides by using five protected Boc-Ser(PO3R2)-OH (R = phenyl, ethyl, methyl, benzyl, t-butyl) derivatives is described.The five Boc-protected derivatives are prepared by a simple three-step synthe

Synthesis of Phosphonates: a Modified Arbuzov Procedure

Reactions of 6-iodogalactosides with either methyl or isopropyl diphenyl phosphite lead to diphenylphosphoryl derivatives; these can be converted by ester exchange into dibenzylphosphoryl derivatives, which are convenient precursors of carbohydrate phosphonic acids.

An improved synthesis of dihydroxyacetone phosphate

An improved procedure has been developed for the synthesis of dihydroxyacetone phosphate (DHAP). Reaction of 2,5-diethoxy-p-dioxane-2,5-dimethanol (1) and the trivalent phosphorylating reagent dibenzyl-N,N-diethylphosphoramidite (DDP) in the presence of 1,2,4-triazole or tetrazole followed by oxidation with H2O2 gave 2,5-diethoxy-p-dioxane-2,5-dimethanol-O-21-O-51-bis(phosphate) tetrabenzyl ester (2) in 98% yield. Compound 2 was then hydrogenated in the presence of H2-Pd/C to give, after neutralization, 2,5-diethoxy-p-dioxane-2,5-dimethanol-O-21-O-51-bis(phosphate) as a stable trisodium salt (3) in 84% yield. Treatment of 3 with Dowex 50 (H+) generates 2 equivalents of DHAP.