3577-87-5

Basic information

• Product Name: METHYL DIPHENYLPHOSPHITE
• Synonyms: METHYL DIPHENYLPHOSPHITE;Phosphorous acid methyldiphenyl ester;Diphenyl Methyl Phosphite
• CAS NO: 3577-87-5
• Molecular Formula: C₁₃H₁₃O₃P
• Molecular Weight: 248.21
• Mol File: 3577-87-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 282.1°Cat760mmHg
• Flash Point: 149.8°C
• Appearance: /Liquid
• Density: g/cm³
• Vapor Pressure: 0.00585mmHg at 25°C
• Solubility: Chloroform, DCM, Methanol, Ethyl Acetate
• Sensitive: Hygroscopic
• CAS DataBase Reference: METHYL DIPHENYLPHOSPHITE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL DIPHENYLPHOSPHITE(3577-87-5)
• EPA Substance Registry System: METHYL DIPHENYLPHOSPHITE(3577-87-5)

Safety Data

• RIDADR: UN3278
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 3577-87-5(Hazardous Substances Data)

Usage

Uses

Diphenyl Methyl Phosphite is an intermediate in the synthesis of organophosphorus compounds as potential pesticides.

InChI:InChI=1/C13H13O3P/c1-14-17(15-12-8-4-2-5-9-12)16-13-10-6-3-7-11-13/h2-11H,1H3

Upstream product

• 67-56-1 methanol 
• 5382-00-3 Diphenyl phosphorochloridite 
• 3279-26-3 methyl dichlorophosphite 
• 108-95-2 phenol 
• 14747-96-7 diphenyl-N,N-diethylphosphoramidite 
• 186581-53-3 diazomethane 
• 101-02-0 triphenyl phosphite 
• 124-41-4 sodium methylate 

Downstream Products

• 2524-64-3 chlorophosphoric acid diphenyl ester 
• 70677-19-9 diphenyl phosphorobromidate 
• 7526-26-3 diphenyl methylphosphonate 
• 33552-07-7 phosphoric acid diphenyl ester vinyl ester 
• 50523-12-1 1-phenyl-eth-1-en-1-yl diphenyl phosphate 
• 50523-18-7 1-(diphenylphosphoryl)propan-2-one 
• 50678-30-3 propen-2-yl diphenyl phosphate 
• 135052-85-6 ((3aR,5S,5aR,8aS,8bR)-2,2,7,7-Tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-ylmethyl)-phosphonic acid diphenyl ester 
• 1026609-92-6 4-(diphenylphosphoryl)-2-fluoro-3-methyl-2-butenenitrile 
• 1059608-77-3 diphenyl pentafluorophenacylphosphonate 
• 1059608-76-2 C₂₆H₂₁O₄P 
• 14862-39-6 diphenyl (2-oxo-2-phenylethyl)phosphonate 
• 181939-33-3 (diphenoxyphosphoryl)methyl p-tolyl sulfide 
• 115-89-9 phosphoric acid methyl ester diphenyl ester 

Relevant articles and documents

Aerobic photooxidation of phosphite esters using diorganotelluride catalysts

Diorganotellurides containing bulky aromatic substituents are found to catalyze the photooxidation of phosphite esters using aerobic oxygen as a terminal oxidant. A Hammett plot with substituted triaryl phosphites yielding p = 2.88 agrees with a nucleophilic oxygen transfer from telluroxide to phosphite.2009 American Chemical Society.

Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and x-ray crystallography

The preparation and identification of symmetric, H3CC(OH)[P(O)(OR)2]2, where R=Me, Et, Pr1, Ph, and non-symmetric, H3CC(OH)[P(O)(OR1)(OR2)][P(O)(OR3)(O R4)], where R1=Me, R2=R3=R4=Ph; R1=R2=R3=Ph, R4=Me; R1=R3=Me, R2=R4=Ph; R1=R2=Et, Pr1, Ph and R3=R4=Me: tetraester derivatives of etidronate have been studied. Compounds were prepared from HP(O)(OR1)(OR2) and AcP(O)(OR3)(OR4) species under reflux. Mechanism studies have been made using HP(O)(OCD3)(OPh) and AcP(O)(OMe)(OPh) as starting materials. 1H, 13C, 31P NMR data and the MS fragmentation data in the gas phase are reported. The solid-state structures are given for three of the compounds, where R=Et, Ph and R1=R2=Ph, R3=R4=Me.

SYNTHESIS OF AN UNREACTIVE YLID DESIGNED AS A -C-P-C-P DIPHOSPHATE ISOSTERE SYNTHON

The complex phosphonium salt 3 was synthesized from bis(hydroxymethyl)phosphinic acid in five steps.The ylid, 2a, produced in situ from 3a, did not react as expected with aldehydes to give the desired phosphonylphosphinyl derivative.Since 2a is actually more basic than the homologous 1, the observed lack of reactivity is apparently not a result of electronic factors.Key words: Analog; diphosphate; phosphinate; phosphonate; phosphonium salt; ylid.