147471-16-7

Upstream product

• 10040-98-9 1-(4-formylphenyl)-1H-imidazole 
• 105-53-3 diethyl malonate 
• 147471-14-5 2-<<4-(1H-imidazol-1-yl)phenyl>methylene>-1,3-propanedioic acid diethyl ester 
• 147471-15-6 2<1-<4-(1H-imidazol-1-yl)phenyl>-2-nitroethyl>-1,3-propanedioic acid diethyl ester 

Downstream Products

• 115621-49-3 1,5-dihydro-4-[4-(1 H-imidazol-1-yl)phenyl]-3-methyl-2 H-pyrrol-2-one 
• 147471-18-9 3-(hydroxymethyl)-4-<4-(1H-imidazol-1-yl)phenyl>-2-pyrrolidinone 
• 1027159-92-7 Methanesulfonic acid 4-(4-imidazol-1-yl-phenyl)-2-oxo-pyrrolidin-3-ylmethyl ester 
• 147471-17-8 4-<4-(1H-imidazol-1-yl)phenyl>-2-oxopyrrolidine-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

(Imidazolylphenyl)pyrrol-2-one inhibitors of cardiac cAMP phosphodiesterase

Seven 3-alkyl-4-aryl-1,5-dihydro-2H-pyrrol-2-ones were prepared as potential inhibitors of cardiac cAMP phosphodiesterase (PDE). The design of these compounds made use of rolipram, a known inhibitor of the brain cAMP PDE isozyme, as a lead structure and w