14772-54-4

Usage

Uses

Used in Pharmaceutical Industry:
(3S,9R,10S,13R,14S,17R)-3-hydroxy-4,4,10,13-tetramethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,5,6,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-14-carbaldehyde is used as a potential pharmaceutical candidate due to its complex molecular structure and the presence of various functional groups. Its steroidal nature and reactivity may offer opportunities for the development of new drugs and therapeutic agents.
Used in Chemical Industry:
In the chemical industry, (3S,9R,10S,13R,14S,17R)-3-hydroxy-4,4,10,13-tetramethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,5,6,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-14-carbaldehyde may be utilized as a building block or intermediate in the synthesis of other complex organic compounds. Its unique structure and functional groups could be valuable in creating new chemical products or improving existing ones.
Further research is needed to fully understand the properties and potential uses of (3S,9R,10S,13R,14S,17R)-3-hydroxy-4,4,10,13-tetramethyl-17-[(2R)-6-met hylheptan-2-yl]-2,3,5,6,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phe nanthrene-14-carbaldehyde in various applications.

InChI:InChI=1/C30H50O2/c1-20(2)9-8-10-21(3)22-14-18-30(19-31)24-11-12-25-27(4,5)26(32)15-16-28(25,6)23(24)13-17-29(22,30)7/h11,19-23,25-26,32H,8-10,12-18H2,1-7H3/t21-,22-,23+,25?,26+,28-,29-,30-/m1/s1

Upstream product

• 4489-02-5 3β-acetoxylanostan-7α-ol 
• 2548-14-3 3β-(Benzoyloxy)-4,4-dimethyl-5α-cholest-8(14)-en-7-one 
• 6384-29-8 3β-(Benzoyloxy)-4,4-dimethyl-5α-cholest-7-ene 
• 141318-26-5 3β-(Benzoyloxy)-7α-hydroxy-4,4-dimethyl-5α-cholestane-14α-carbonitrile 
• 141273-64-5 3β-(Benzoyloxy)-4,4-dimethyl-7-oxo-5α-cholestane-14α-carbonitrile 
• 2811-33-8 3β-(Benzoyloxy)-4,4-dimethyl-8α,14α-epoxy-5α-cholestan-7-one 
• 4543-21-9 Acetic acid (3S,5R,7R,8R,9S,10R,13R,14R,17R)-14-cyano-17-((R)-1,5-dimethyl-hexyl)-7-methanesulfonyloxy-4,4,10,13-tetramethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 4573-23-3 Acetic acid (3S,5R,7R,8R,9S,10R,13R,14R,17R)-17-((R)-1,5-dimethyl-hexyl)-7-hydroxy-14-(hydroxyimino-methyl)-4,4,10,13-tetramethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 5713-42-8 3β-acetoxy-4,4,14α-trimethyl-5α-cholestan-7-one 
• 141273-65-6 3β-(Benzoyloxy)-4,4-dimethyl-7α-<(methylsulfonyl)oxy>-5α-cholestane-14α-carbonitrile 
• 6384-28-7 4,4-dimethyl-5α-cholest-7-en-3β-ol 
• 4489-03-6 3β-acetoxylanostan-7α,32-oxide 
• 5713-35-9 lanost-7-ene-3β,32-diol 
• 4573-22-2 3β-acetoxylanost-7α-nitrite 

Relevant academic research and scientific papers

Synthesis of 14-&α-Aminomethyl substituted Lanosterol Derivatives; Inhibitors of Fungal Ergosterol Biosynthesis

Several 14-α-aminomethyl-substituted lanosterol derivatives have been synthesized involving a complete Δ7,8 to Δ8,9 isomerization; these compounds are inhibitors of fungal ergosterol biosynthesis and are active against intact Candida and dermatophyte strains.

Regioselective Synthesis of Δ6-, Δ7-, and Δ8-14α-Cyanosterol Derivatives: Versatile Precursors to 14α-Demethylase Inhibitors

The efficient preparation of 3β-(benzoyloxy)-4,4-dimethyl-5α-cholest-8(14)-en-7-one (4a) and 3β-(benzyloxy)-5α-ergosta-8(14),22-dien-7-one (4b) and their conversion to Δ6-, Δ7- or Δ8-14α-functionalized sterols is reported.

STEROIDAL 14ALPHA-CARBOXY-ALKYL DERIVATIVES AS REGULATORS OF HMG-COA REDUCTASE

New 14α-carboxyalkyl sterols are regulators of HMG-CoA reductase and inhibitors of mammalian 14α-methyl demethylase and are useful in lowering serum cholesterol levels and treating fungal infections.